ArticleDevelopmental cognitive neuroscience2020
Adolescent development of inhibitory control and substance use vulnerability: A longitudinal neuroimaging study.
Article in Developmental cognitive neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 3 of them syntheses that pooled it.
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Who cites it
22 citing papers in PubMed, 3 syntheses or guidelines pooled it, 40 citations in OpenAlex.
- Emotion processing in youths with conduct problems: an fMRI meta-analysis.Translational psychiatry · 2023Pooled it
- Inhibitory Control Development: A Network Neuroscience Perspective.Frontiers in psychology · 2022Pooled it
- Meta-analysis and review of functional neuroimaging differences underlying adolescent vulnerability to substance use.NeuroImage · 2020Pooled it
- Developmental variation in basal ganglia tissue iron, neurocognitive functioning, and impulsivity is associated with substance use trajectories in youth.Nature communications · 2026Article
- Self-reported impulsivity, task-based inhibitory control, and early sipping behaviors as longitudinal predictors of adolescent alcohol use and problems in the ABCD Study.medRxiv : the preprint server for health sciences · 2026Article
- Neurobehavioral correlates of inhibitory control in youth at-risk for early low-level alcohol use initiation: neuroimaging findings from the ABCD study.Frontiers in psychiatry · 2026Article
- The role of the salience network in adolescent impulsivity using memory tasks and neuroimaging.Communications medicine · 2025Article
- Developmental variation in dopamine neurobiology, neurocognitive functioning, and impulsivity shape substance use trajectories in youth.bioRxiv : the preprint server for biology · 2025Article
- Development of Self-Reported Reward Responsiveness and Inhibitory Control and the Role of Clinical and Neural Predictors.Journal of personality · 2025Article
- Investigating risk factor and consequence accounts of executive functioning impairments in psychopathology: an 8-year study of at-risk individuals in Brazil.Psychological medicine · 2025Article
- Integrative cognitive neuropsychological program emphasizing brain response to enhance inhibitory control among substance abusers at the alternative rehabilitation communities in Eastern Thailand.Frontiers in psychiatry · 2025Article
- Impact of behavioral inhibitory control and startle reactivity to uncertain threat on youth suicide risk.Psychophysiology · 2025Article
- The Youth Risk Index: psychometrics, predicting the initiation of early adolescent substance use, and the breadth of liability detected.Frontiers in child and adolescent psychiatry · 2025Article
- Psychopathology as long-term sequelae of maltreatment and socioeconomic disadvantage: Neurocognitive development perspectives.Development and psychopathology · 2024Article
- A canonical trajectory of executive function maturation from adolescence to adulthood.Nature communications · 2023Article
- Loss and Frontal Striatal Reactivities Characterize Alcohol Use Severity and Rule-Breaking Behavior in Young Adult Drinkers.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2022Article
- Neurobehavioral maturation of motor response inhibition in adolescence - A narrative review.Neuroscience and biobehavioral reviews · 2022Review
- Contributions of dopamine-related basal ganglia neurophysiology to the developmental effects of incentives on inhibitory control.Developmental cognitive neuroscience · 2022Article
- Brain Activity During Antisaccades to Faces in Adolescence.Cerebral cortex communications · 2021Article
- Risks versus consequences of adolescent and young adult substance use: A focus on executive control.Current addiction reports · 2020Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
Previous research indicates that risk for substance use is associated with poor inhibitory control. However, it remains unclear whether at-risk youth follow divergent patterns of inhibitory control development. As part of the longitudinal National Consortium on Adolescent Neurodevelopment and Alcohol study, participants (N = 113, baseline age: 12-21) completed a rewarded antisaccade task during fMRI, with up to three time points. We examined whether substance use risk factors, including psychopathology (externalizing, internalizing) and family history of substance use disorder, were associated with developmental differences in inhibitory control performance and BOLD activation. Among the examined substance use risk factors, only externalizing psychopathology exhibited developmental differences in inhibitory control performance, where higher scores were associated with lower correct response rates (p = .013) and shorter latencies (p < .001) in early adolescence that normalized by late adolescence. Neuroimaging results revealed higher externalizing scores were associated with developmentally-stable hypo-activation in the left middle frontal gyrus (p < .05 corrected), but divergent developmental patterns of posterior parietal cortex activation (p < .05 corrected). These findings suggest that early adolescence may be a unique period of substance use vulnerability via cognitive and phenotypic disinhibition.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.