Evidence map›Paper›PMID 32452404›Full record

ArticlePlacenta2020

Placental MRI: Effect of maternal position and uterine contractions on placental BOLD MRI measurements.

Esra Abaci Turk, S Mazdak Abulnaga, Jie Luo, Jeffrey N Stout, Henry A Feldman, Ata Turk, Borjan Gagoski, Lawrence L Wald, Elfar Adalsteinsson, Drucilla J Roberts and 5 more

Erratum issued Registry-linked trialOpen access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Placenta, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT06290232 (Fetoscopic Laser Photocoagulation in Management of Vasa Previa - FLUMEN Study), which is not on this map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
3.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06290232 nawithdrawnnot on this mapstarted 2026, after this paper: background citation

Fetoscopic Laser Photocoagulation in Management of Vasa Previa - FLUMEN Study

TypeinterventionalSponsorBoston Children's HospitalRan2026 to 2028Enrolled0ConditionsVasa Previa, Pregnancy Complications, Maternal, ProcedureArmsFetoscopic Laser Photocoagulation
3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 49 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. Toward Clinical Implementation of Magnetic Resonance Imaging for Placental Function.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2025
    Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Shape-aware Segmentation of the Placenta in BOLD Fetal MRI Time Series.The journal of machine learning for biomedical imaging · 2023
    Article
  11. Real-time fetal brain tracking for functional fetal MRI.Magnetic resonance in medicine · 2023
    Article
  12. Article
  13. Review
  14. Article
  15. Developments in functional imaging of the placenta.The British journal of radiology · 2023
    Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Fetal Neuroimaging Updates.Magnetic resonance imaging clinics of North America · 2021
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

15 authors at 8 institutions in 2 countries.

Esra Abaci TurkFetal-Neonatal Neuroimaging & Developmental Science Center, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA. Electronic address: esra.abaciturk@childrens.harvard.edu.
S Mazdak AbulnagaComputer Science and Artificial Intelligence Laboratory (CSAIL), Massachusetts Institute of Technology, Cambridge, MA, USA.
Jie LuoFetal-Neonatal Neuroimaging & Developmental Science Center, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA; School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, China.
Jeffrey N StoutFetal-Neonatal Neuroimaging & Developmental Science Center, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.
Henry A FeldmanInstitutional Centers for Clinical and Translational Research, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.
Ata TurkElectrical Computer Engineering Department, Boston University, Boston, MA, USA.
Borjan GagoskiFetal-Neonatal Neuroimaging & Developmental Science Center, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.
Lawrence L WaldDepartment of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge, MA, USA; Radiology, Harvard Medical School, Boston, MA, United States; Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, United States.
Elfar AdalsteinssonDepartment of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge, MA, USA; Harvard-MIT Health Sciences and Technology; Massachusetts Institute of Technology, Cambridge, MA, USA; Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, MA, USA.
Drucilla J RobertsDepartment of Pathology, Massachusetts General Hospital, Boston, MA, USA.
Carolina BibboMaternal Fetal Medicine, Brigham and Women's Hospital, Boston, MA, USA.
Julian N RobinsonMaternal Fetal Medicine, Brigham and Women's Hospital, Boston, MA, USA.
Polina GollandComputer Science and Artificial Intelligence Laboratory (CSAIL), Massachusetts Institute of Technology, Cambridge, MA, USA; Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge, MA, USA.
P Ellen GrantFetal-Neonatal Neuroimaging & Developmental Science Center, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.
William H BarthMaternal-Fetal Medicine, Obstetrics and Gynecology, Massachusetts General Hospital, Boston, MA, USA.
Boston Children's Hospital · USBrigham and Women's Hospital · USHarvard University · USMassachusetts General Hospital · USMassachusetts Institute of Technology · USAthinoula A. Martinos Center for Biomedical Imaging · USBoston University · USHarvard–MIT Division of Health Sciences and Technology · US

Funding

Training and DisseminationP41EB015902 · NIBIB · BRIGHAM AND WOMEN'S HOSPITAL · PI KIKINIS, RON, WESTIN, CARL-FREDRIK · 2012 to 2022
$20.9M
Advanced Fetal ImagingR01EB017337 · NIBIB · BOSTON CHILDREN'S HOSPITAL · PI ADALSTEINSSON, ELFAR, GRANT, PATRICIA ELLEN · 2014 to 2018
$6.2M
Noninvasive Realtime Assessment of Placental Structure and Function with Novel MR Imaging MethodsU01HD087211 · NICHD · BOSTON CHILDREN'S HOSPITAL · PI GRANT, PATRICIA ELLEN, WALD, LAWRENCE L · 2015 to 2015
$4.9M
Novel MRI Assessment of Placental Structure and Function Throughout PregnancyR01HD100009 · NICHD · BOSTON CHILDREN'S HOSPITAL · PI ADALSTEINSSON, ELFAR, GRANT, PATRICIA ELLEN · 2019 to 2023
$3.6M
NIBIB NIH HHS P41 EB015902NIBIB NIH HHS R01 EB017337NICHD NIH HHS R01 HD100009NICHD NIH HHS U01 HD087211
6 · The paper itself

Abstract

introductionBefore using blood-oxygen-level-dependent magnetic resonance imaging (BOLD MRI) during maternal hyperoxia as a method to detect individual placental dysfunction, it is necessary to understand spatiotemporal variations that represent normal placental function. We investigated the effect of maternal position and Braxton-Hicks contractions on estimates obtained from BOLD MRI of the placenta during maternal hyperoxia.

methodsFor 24 uncomplicated singleton pregnancies (gestational age 27-36 weeks), two separate BOLD MRI datasets were acquired, one in the supine and one in the left lateral maternal position. The maternal oxygenation was adjusted as 5 min of room air (21% O

resultsIn mothers without contractions, increases in global placental R

conclusionBoth maternal position and Braxton-Hicks contractions significantly affect global and regional changes in placental R

Indexed as

Patient PositioningAdultFemaleHumansMagnetic Resonance ImagingPlacentaPlacenta DiseasesPregnancyUterine ContractionBOLD MRIBraxton-Hicks contractionMaternal hyperoxiaMaternal positionPlacental MRI

Identifiers

PMID32452404
PMCPMC7358045
OpenAlexW3018514935

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.