Evidence map›Paper›PMID 32452384›Full record

ArticleeLife2020

A molecular filter for the cnidarian stinging response.

Keiko Weir, Christophe Dupre, Lena van Giesen, Amy S-Y Lee, Nicholas W Bellono

Abstract read
In one paragraph

Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Sleeping upside-down: Knockdown of a sleep-associated gene induces daytime sleep in the jellyfishProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  8. Evolution of Sensory Receptors.Annual review of cell and developmental biology · 2024
    Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Conserved biophysical features of the CaThe Journal of biological chemistry · 2020
    Article
  16. Parasitology · 2020
    Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Keiko WeirDepartment of Molecular and Cellular Biology, Harvard University, Cambridge, United States.ORCID 0000-0002-2501-9352
Christophe DupreDepartment of Molecular and Cellular Biology, Harvard University, Cambridge, United States.ORCID 0000-0002-5929-8492
Lena van GiesenDepartment of Molecular and Cellular Biology, Harvard University, Cambridge, United States.
Amy S-Y LeeDepartment of Biology, Brandeis University, Waltham, United States.ORCID 0000-0002-4121-0720
Nicholas W BellonoDepartment of Molecular and Cellular Biology, Harvard University, Cambridge, United States.ORCID 0000-0002-0829-9436

Funding

A Facility to Generate Connectomics InformationU24NS109102 · NINDS · HARVARD UNIVERSITY · PI LICHTMAN, JEFF W · 2018 to 2023
$6.5M
Molecular Mechanisms of Integrative Signal TransductionR35GM142697 · NIGMS · HARVARD UNIVERSITY · PI Nicholas Bellono · 2021 to 2026
$2.6M
Molecular mechanisms of sensory transduction in the gutR00DK115879 · NIDDK · HARVARD UNIVERSITY · PI BELLONO, NICHOLAS · 2018 to 2020
$747k
Molecular Mechanisms of the sea anemone stinging responseF31NS117055 · NINDS · HARVARD UNIVERSITY · PI WEIR, KEIKO · 2020 to 2020
$40k
NIDDK NIH HHS R00 DK115879NIGMS NIH HHS R35 GM142697NIH HHS P2SKP3_187684NINDS NIH HHS F31 NS117055NINDS NIH HHS U24 NS109102Swiss National Science Foundation P2SKP3-187684Swiss National Science Foundation P400PB-180894
6 · The paper itself

Abstract

All animals detect and integrate diverse environmental signals to mediate behavior. Cnidarians, including jellyfish and sea anemones, both detect and capture prey using stinging cells called nematocytes which fire a venom-covered barb via an unknown triggering mechanism. Here, we show that nematocytes from

Indexed as

Mechanotransduction, CellularAnimalsCalcium Channels, N-TypeNematocystSea AnemonesCalcium Channels, N-Typecalcium signalingcnidarianion channelmolecular biophysicsnematocystneuroethologyneurosciencesensory physiologystructural biology

Identifiers

PMID32452384
PMCPMC7250568

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.