Evidence map›Paper›PMID 32452171›Full record

ArticleJournal of biomedical optics2020

Laser speckle contrast imaging system using nanosecond pulse laser source.

Yuemei Zhao, Kang Wang, Weitao Li, Huan Zhang, Zhiyu Qian, Yangyang Liu

Open access · goldAbstract read
In one paragraph

Article in Journal of biomedical optics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Yuemei ZhaoNanjing University of Aeronautics and Astronautics, Department of Biomedical Engineering, Nanjing, China.
Kang WangNanjing University of Aeronautics and Astronautics, Department of Biomedical Engineering, Nanjing, China.
Weitao LiNanjing University of Aeronautics and Astronautics, Department of Biomedical Engineering, Nanjing, China.
Huan ZhangNanjing University of Aeronautics and Astronautics, Department of Biomedical Engineering, Nanjing, China.
Zhiyu QianNanjing University of Aeronautics and Astronautics, Department of Biomedical Engineering, Nanjing, China.
Yangyang LiuNanjing Institute of Technology, Nanjing, China.
Nanjing University of Aeronautics and Astronautics · CNNanjing Institute of Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

significanceNanosecond-pulsed laser has proven to be used to obtain the velocity of blood using the speckle contrast method. Without the scanning time, it has potential for achieving fast two-dimensional blood flow images in a photoacoustic imaging system with the same pulsed laser.

aimOur study aimed to evaluate the qualities of regional cerebral blood flow (rCBF) obtained in a laser speckle contrast imaging (LSCI) system using continuous wave (cw) and nanosecond pulse laser sources. APPROACH: First, a LSCI system consisting of a cw laser with a wavelength of 632.8 nm and a cw laser/nanosecond pulse laser with a wavelength of 532 nm was developed. This system was used to obtain rCBF images of mouse in vivo with two different laser sources.

resultsContinuous wave lasers (532 and 632.8 nm) show different imaging characteristics for rCBF imaging. The rCBF images obtained using 532-nm nanosecond pulse laser showed higher resolution than those using 532-nm cw laser. There was no significant difference in the results using nanosecond pulse laser among various pulse widths or repetition rates.

conclusionsIt is proved that a nanosecond pulse laser could be used for LSCI.

Indexed as

LasersLaser Speckle Contrast ImagingAnimalsCerebrovascular CirculationDiagnostic ImagingMiceSpectrum Analysiscerebral blood flowcontinuous wavelaser speckle contrast imaging

Identifiers

PMID32452171
PMCPMC7247735
OpenAlexW3027637407

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.