Evidence map›Paper›PMID 32451950›Full record

ArticleAdvances in therapy2020

Healthcare Resources Utilization and Costs of Patients with Non-IPF Progressive Fibrosing Interstitial Lung Disease Based on Insurance Claims in the USA.

Amy L Olson, Toby M Maher, Valentina Acciai, Baher Mounir, Manuel Quaresma, Leila Zouad-Lejour, Christopher D Wells, Lou De Loureiro

Open access · hybridAbstract read
In one paragraph

Article in Advances in therapy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.

  1. Economic burden and cost drivers of interstitial lung disease: a systematic review.The European journal of health economics : HEPAC : health economics in prevention and care · 2026
    Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Burden of illness in progressive fibrosing interstitial lung disease.Journal of managed care & specialty pharmacy · 2022
    Article
  10. Article
  11. Article
  12. Review
  13. Observational
  14. Article
  15. Article
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 3 countries.

Amy L OlsonNational Jewish Health, Denver, USA. OlsonA@NJHealth.org.
Toby M MaherNIHR Respiratory Clinical Research Facility, Royal Brompton Hospital, London, UK.
Valentina AcciaiBoehringer Ingelheim Corporation, Ingelheim am Rhein, Germany.
Baher MounirBoehringer Ingelheim Corporation, Ingelheim am Rhein, Germany.
Manuel QuaresmaBoehringer Ingelheim Corporation, Ingelheim am Rhein, Germany.
Leila Zouad-LejourBoehringer Ingelheim Corporation, Ingelheim am Rhein, Germany.
Christopher D WellsDecision Resources Group, Burlington, USA.
Lou De LoureiroDecision Resources Group, Burlington, USA.
Boehringer Ingelheim (Germany) · DEImperial College London · GBUniversity of Colorado Denver · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionIdiopathic pulmonary fibrosis (IPF) is the classic progressive fibrosing interstitial lung disease (ILD), but some patients with ILDs other than IPF also develop a progressive fibrosing phenotype (PF-ILD). Information on use and cost of healthcare resources in patients with PF-ILD is limited.

methodsWe used USA-based medical insurance claims (2014-2016) to assess use and cost of healthcare resources in PF-ILD. Patients with at least two ILD claims and at least one pulmonologist visit were considered to have ILD. Pulmonologist visit frequency was used as a proxy to identify PF-ILD (at least four visits in 2016, or at least three more visits in 2016 vs. 2014).

resultsOf 2517 patients with non-IPF ILD, 15% (n = 373) had PF-ILD. Mean annual medical costs associated with ILD claims were $35,364 in patients with non-IPF PF-ILD versus $20,211 in the non-IPF ILD population. In 2016, patients with non-IPF PF-ILD made more hospital ILD claims than patients with non-IPF ILD (10.5 vs. 4.7).

conclusionsThese findings suggest higher disease severity and overall healthcare use for patients with a non-IPF ILD manifesting a progressive fibrosing phenotype (non-IPF PF-ILD).

Indexed as

AdultAgedAged, 80 and overDisease ProgressionFemaleForecastingHealth Care CostsHumansIdiopathic Pulmonary FibrosisInsurance Claim ReviewLung Diseases, InterstitialMaleMiddle AgedPatient Acceptance of Health CareUnited StatesCostsFibrosisHealthcareHospitalizationInterstitial lung diseaseLungPF-ILDProgressive fibrosis

Identifiers

PMID32451950
PMCPMC7467408
OpenAlexW3031318752

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.