Evidence map›Paper›PMID 32451813›Full record

ArticleJournal of assisted reproduction and genetics2020

Chromosomal polymorphisms associated with reproductive outcomes after IVF-ET.

Sai-Jiao Li, Yan-Xiang Cheng, Ye-Shang, Dan-Ni Zhou, Yin Zhang, Tai-Lang Yin, Jing Yang

Open access · hybridAbstract read
In one paragraph

Article in Journal of assisted reproduction and genetics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Sai-Jiao LiReproductive Medical Center, Renmin Hospital of Wuhan University, No. 238 JieFang Road, Wuhan, 430060, People's Republic of China.
Yan-Xiang ChengGynecology Department, Renmin Hospital of Wuhan University, No. 238 JieFang Road, Wuhan, 430060, People's Republic of China.
Ye-ShangReproductive Medical Center, Renmin Hospital of Wuhan University, No. 238 JieFang Road, Wuhan, 430060, People's Republic of China.
Dan-Ni ZhouReproductive Medical Center, Renmin Hospital of Wuhan University, No. 238 JieFang Road, Wuhan, 430060, People's Republic of China.
Yin ZhangReproductive Medical Center, Renmin Hospital of Wuhan University, No. 238 JieFang Road, Wuhan, 430060, People's Republic of China.
Tai-Lang YinReproductive Medical Center, Renmin Hospital of Wuhan University, No. 238 JieFang Road, Wuhan, 430060, People's Republic of China.
Jing YangReproductive Medical Center, Renmin Hospital of Wuhan University, No. 238 JieFang Road, Wuhan, 430060, People's Republic of China. dryangqing@hotmail.com.
Renmin Hospital of Wuhan University · CNWuhan University · CN

Funding

China Scholarship Council 201806275007National Natural Science Foundation of China 81701412Natural Science Foundation of Hubei Province 2018CFB491
6 · The paper itself

Abstract

purposeThis study aimed to investigate the effect of the detail type of chromosomal polymorphisms (1/9/16qh

methodsA total of 1335 infertile couples undergoing IVF/ICSI were enrolled and comprehensively analyzed the correlation between three detail types of chromosomal polymorphisms (1/9/16qh

resultsBoth the inv(9) and D/G group chromosomal polymorphisms related to female infertility significantly lead to a lower 2PN cleavage rate (86.44% vs. 97.58% and 90.67% vs. 97.58%, respectively, P < 0.05) undergoing IVF insemination, the inv(9) adversely increasing the early miscarriage rate, either undergoing IVF (21.4% vs. 3.0%, P < 0.05) or ICSI (50.0% vs. 2.0%, P < 0.05) insemination, female carriers (23.08% vs. 2.87%, P < 0.05) or male carriers (44.44% vs. 2.87%, P < 0.05). For D/G groups, ICSI insemination may increase the implantation rate (44.8% vs. 23.69%, P < 0.05) and clinical pregnancy rate (78.6% vs. 40.65%, P < 0.05). 1/9/16qh

conclusionsOur study suggests that chromosome karyotype analysis is necessary for IVF patients in clinical practice; we should afford individual genetic counseling suggestion according to the polymorphism types.

Indexed as

Fertilization in VitroPolymorphism, GeneticAbortion, SpontaneousAdultChromosomes, HumanEmbryo TransferFemaleHumansInfertilityKaryotypingMaleOocyte RetrievalPregnancyPregnancy RateRetrospective StudiesSperm Injections, IntracytoplasmicChromosomal polymorphisminv(9)IVF-ETMiscarriage

Identifiers

PMID32451813
PMCPMC7376992
OpenAlexW3031293378

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.