Observational studyIntensive care medicine2020
Prognostic relevance and inter-observer reliability of chest-imaging in pediatric ARDS: a pediatric acute respiratory distress incidence and epidemiology (PARDIE) study.
Observational study in Intensive care medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 30 citations in OpenAlex.
- Biomarkers for Pediatric Acute Respiratory Distress Syndrome: A Systematic Review.Journal of inflammation research · 2026Review
- Are lung ultrasound and chest radiograph equally reliable for neonatal imaging? A scoping review.European journal of pediatrics · 2025Article
- Joint classification and segmentation for an interpretable diagnosis of acute respiratory distress syndrome from chest x-rays.Journal of medical imaging (Bellingham, Wash.) · 2023Article
- A Web-Based Platform for the Automatic Stratification of ARDS Severity.Diagnostics (Basel, Switzerland) · 2023Article
- Exome sequencing contributes to identify comorbidities in a rare case of infant ARDS induced by the CD40LG mutation.BMC medical genomics · 2022Article
- Mechanical power in pediatric acute respiratory distress syndrome: a PARDIE study.Critical care (London, England) · 2022Observational
- Clinical Outcome Discrimination in Pediatric ARDS by Chest Radiograph Severity Scoring.Canadian respiratory journal · 2022Article
- Performance of acute respiratory distress syndrome definitions in a high acuity paediatric intensive care unit.Respiratory research · 2021Article
- Paediatrics: how to manage acute respiratory distress syndrome.Drugs in context · 2021Review
- Corticosteroid treatment in severe COVID-19 patients with acute respiratory distress syndrome.The Journal of clinical investigation · 2020Observational
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors at 10 institutions in 4 countries.
Funding
Abstract
purposeDefinitions of acute respiratory distress syndrome (ARDS) include radiographic criteria, but there are concerns about reliability and prognostic relevance. This study aimed to evaluate the independent relationship between chest imaging and mortality and examine the inter-rater variability of interpretations of chest radiographs (CXR) in pediatric ARDS (PARDS).
methodsProspective, international observational study in children meeting Pediatric Acute Lung Injury Consensus Conference (PALICC) criteria for PARDS, which requires new infiltrate(s) consistent with pulmonary parenchymal disease, without mandating bilateral infiltrates. Mortality analysis focused on the entire cohort, whereas inter-observer variability used a subset of patients with blinded, simultaneous interpretation of CXRs by intensivists and radiologists.
resultsBilateral infiltrates and four quadrants of alveolar consolidation were associated with mortality on a univariable basis, using CXRs from 708 patients with PARDS. For patients on either invasive (IMV) or non-invasive ventilation (NIV) with PaO
conclusionBilateral infiltrates and quadrants of alveolar consolidation are associated with mortality only for those with PF ratio ≤ 100, although there is high- inter-rater variability in these chest-x ray parameters.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.