ArticleNature medicine2020
Chemotherapy-induced ileal crypt apoptosis and the ileal microbiome shape immunosurveillance and prognosis of proximal colon cancer.
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In one paragraph
Article in Nature medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 131 papers, 2 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
131citing papers in PubMed, 2 pooled it
10.3field-weighted citation impact, top 1% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
131 citing papers in PubMed, 2 syntheses or guidelines pooled it, 192 citations in OpenAlex.
- Gut microbiota-associated predictors as biomarkers of neoadjuvant treatment response in rectal cancer-a systematic review.British journal of cancer · 2026Pooled it
- Effect ofFrontiers in pharmacology · 2025Pooled it
- Chenopodium Quinoa's Ingredients Contribute to the Gut Microbiota's Metabolic Adaptations on Carbohydrate Metabolism.Plant foods for human nutrition (Dordrecht, Netherlands) · 2024Trial
- Subclinical cholestasis is a hallmark of gut dysbiosis causing resistance to cancer immunotherapy.Cancer cell · 2026Article
- A Microbial Lipid-ATP Synthase Axis Fuels NK Cell Antitumor Activity.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Harnessing the microbiome for cancer therapy.Nature reviews. Microbiology · 2026Review
- Gut microbiota and cancer immunotherapy: from dysbiosis to personalized immune checkpoint blockade optimization.Folia microbiologica · 2026Review
- Immunogenic cell death as a cornerstone for combination therapies with immune checkpoint blockade.Molecular cancer · 2026Review
- Synergistic Interactions Between Gut and Intratumoral Microbiota: A New Perspective on the Oncogenesis and Treatment of Colorectal Cancer.Digestive diseases and sciences · 2026Review
- Inhibition of DDX5-Mediated G-Quadruplex Unwinding in the β-Catenin 5'-UTR by Magnesium Isoglycyrrhizinate Alleviates Chemotherapy-Induced Intestinal Injury.Research (Washington, D.C.) · 2026Article
- Metabolism-Driven Modulation by the Human Microbiota: Implications for Cancer Therapy and Emerging Strategies.Advances in experimental medicine and biology · 2026Review
- Chemotherapy-driven intestinal dysbiosis and indole-3-propionic acid rewire myelopoiesis to promote a metastasis-refractory state.Nature communications · 2025Article
- Immune-microbiota dysregulation in maintenance hemodialysis: a 16S rRNA sequencing-based analysis of gut flora and T cell profiles.Renal failure · 2025Article
- Surrogate markers of intestinal dysfunction associated with survival in advanced cancers.Oncoimmunology · 2025Article
- Review
- The microbiota in radiotherapy-induced cancer immunosurveillance.Nature reviews. Clinical oncology · 2025Review
- Bacteriophages, Antibiotics and Probiotics: Exploring the Microbial Battlefield of Colorectal Cancer.International journal of molecular sciences · 2025Review
- Mitigation of chemotherapy-induced gut dysbiosis and diarrhea by supplementation with heat-killed Bacteroides fragilis.BMC medicine · 2025Article
- Multidimensional differences of right- and left-sided colorectal cancer and their impact on targeted therapies.NPJ precision oncology · 2025Review
- Distribution of gut microbiota across intestinal segments and their impact on human physiological and pathological processes.Cell & bioscience · 2025Review
71 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
46 authors at 11 institutions in 6 countries.
Maria Paula RobertiGustave Roussy Cancer Campus (GRCC), Villejuif, France.ORCID http://orcid.org/0000-0001-5788-6840
Satoru YonekuraGustave Roussy Cancer Campus (GRCC), Villejuif, France.ORCID http://orcid.org/0000-0003-4047-3016
Connie P M DuongGustave Roussy Cancer Campus (GRCC), Villejuif, France.ORCID http://orcid.org/0000-0002-9067-8557
Marion PicardGustave Roussy Cancer Campus (GRCC), Villejuif, France.
Gladys FerrereGustave Roussy Cancer Campus (GRCC), Villejuif, France.
Maryam Tidjani AlouGustave Roussy Cancer Campus (GRCC), Villejuif, France.
Conrad RauberGustave Roussy Cancer Campus (GRCC), Villejuif, France.
Valerio IebbaGustave Roussy Cancer Campus (GRCC), Villejuif, France.ORCID http://orcid.org/0000-0002-0716-306X
Christian H K LehmannDepartment of Dermatology, Laboratory of Dendritic Cell Biology, Medical Immunology Campus Erlangen, University Hospital of Erlangen, Friedrich-Alexander-University (FAU) of Erlangen-Nürnberg, Erlangen, Germany.ORCID http://orcid.org/0000-0001-5927-9761
Lukas AmonDepartment of Dermatology, Laboratory of Dendritic Cell Biology, Medical Immunology Campus Erlangen, University Hospital of Erlangen, Friedrich-Alexander-University (FAU) of Erlangen-Nürnberg, Erlangen, Germany.
Diana DudziakDepartment of Dermatology, Laboratory of Dendritic Cell Biology, Medical Immunology Campus Erlangen, University Hospital of Erlangen, Friedrich-Alexander-University (FAU) of Erlangen-Nürnberg, Erlangen, Germany.
Lisa DerosaGustave Roussy Cancer Campus (GRCC), Villejuif, France.
Bertrand RoutyGustave Roussy Cancer Campus (GRCC), Villejuif, France.
Caroline FlamentGustave Roussy Cancer Campus (GRCC), Villejuif, France.
Corentin RichardDepartment of Medical Oncology, Center GF Leclerc, Dijon, France.ORCID http://orcid.org/0000-0001-9732-0219
Romain DaillèreGustave Roussy Cancer Campus (GRCC), Villejuif, France.
Aurélie FluckigerGustave Roussy Cancer Campus (GRCC), Villejuif, France.
Isabelle Van SeuningenInserm UMR-S 1172, Jean-Pierre Aubert Research Center, CHU Lille, University of Lille, Lille, France.ORCID http://orcid.org/0000-0002-3131-2694
Mathias ChamaillardLaboratory of Cell Physiology, INSERM U1003, University of Lille, Lille, France.
Audrey VincentInserm UMR-S 1172, Jean-Pierre Aubert Research Center, CHU Lille, University of Lille, Lille, France.ORCID http://orcid.org/0000-0003-0058-2058
Stephanie KourulaMolecular Signaling and Cell Death Unit, VIB Inflammation Research Center, Ghent, Belgium.
Paule OpolonGustave Roussy Cancer Campus (GRCC), Villejuif, France.
Pierre LyGustave Roussy Cancer Campus (GRCC), Villejuif, France.
Eugénie PizzatoGustave Roussy Cancer Campus (GRCC), Villejuif, France.
Sonia BecharefGustave Roussy Cancer Campus (GRCC), Villejuif, France.
Juliette PailletUniversité Paris-Saclay, Le Kremlin-Bicêtre cedex, France.ORCID http://orcid.org/0000-0001-7118-7165
Christophe KleinEquipe Labellisée par la Ligue Contre le Cancer, Université de Paris, Sorbonne Université, INSERM U1138, Centre de Recherche des Cordeliers, Paris, France.ORCID http://orcid.org/0000-0001-8015-287X
Florence MarliotLaboratory of Integrative Cancer Immunology, INSERM U1138, Centre de Recherche des Cordeliers, Paris, France.
Filippo PietrantonioMedical Oncology Department, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
Stéphane BenoistService de Chirurgie Digestive et Oncologique, Hôpital Bicêtre, Le Kremlin-Bicêtre, France.
Jean-Yves ScoazecDepartement de Biologie et Pathologie Médicales, Gustave Roussy Cancer Campus, Villejuif, France.ORCID http://orcid.org/0000-0003-1604-6823
Peggy DartiguesDepartement de Biologie et Pathologie Médicales, Gustave Roussy Cancer Campus, Villejuif, France.
Antoine HollebecqueDepartement de Médicine Oncologique, Gustave Roussy Cancer Campus, Villejuif, France.
David MalkaDepartement de Médicine Oncologique, Gustave Roussy Cancer Campus, Villejuif, France.
Franck PagèsLaboratory of Integrative Cancer Immunology, INSERM U1138, Centre de Recherche des Cordeliers, Paris, France.
Jérôme GalonLaboratory of Integrative Cancer Immunology, INSERM U1138, Centre de Recherche des Cordeliers, Paris, France.ORCID http://orcid.org/0000-0001-9635-1339
Ivo Gomperts BonecaUnit Biology and Genetics of the Bacterial Cell Wall, Institut Pasteur Paris, Paris, France.
Patricia LepageMicalis Institute, INRA, AgroParisTech, Université Paris-Saclay, Jouy-en-Josas, France.
Bernard RyffelMolecular Immunology and Embryology, UMR 7355, CNRS, University of Orleans, Orléans, France.
Didier RaoultUnité des Rickettsies, Faculté de Médecine, Université de la Méditerranée, Marseille, France.
Alexander EggermontGustave Roussy Cancer Campus (GRCC), Villejuif, France.
Tom Vanden BergheMolecular Signaling and Cell Death Unit, VIB Inflammation Research Center, Ghent, Belgium.
François GhiringhelliDepartment of Medical Oncology, Center GF Leclerc, Dijon, France.
Peter VandenabeeleMolecular Signaling and Cell Death Unit, VIB Inflammation Research Center, Ghent, Belgium.ORCID http://orcid.org/0000-0002-6669-8822
Guido KroemerEquipe Labellisée par la Ligue Contre le Cancer, Université de Paris, Sorbonne Université, INSERM U1138, Centre de Recherche des Cordeliers, Paris, France.ORCID http://orcid.org/0000-0002-9334-4405
Laurence ZitvogelGustave Roussy Cancer Campus (GRCC), Villejuif, France. laurence.zitvogel@gustaveroussy.fr.ORCID http://orcid.org/0000-0003-1596-0998
Inserm · FRInstitut Gustave Roussy · FRFriedrich-Alexander-Universität Erlangen-Nürnberg · DEGhent University · BECentre Georges François Leclerc · FRAgroParisTech · FRBicêtre Hospital · FRInstitut de Neurobiologie de la Méditerranée · FRKarolinska University Hospital · SEUniversité d'Orléans · FRUniversity of Milan · IT
Funding
No grant is acknowledged in the PubMed record.
Abstract
The prognosis of colon cancer (CC) is dictated by tumor-infiltrating lymphocytes, including follicular helper T (T
Indexed as
AdenocarcinomaAdultAgedAged, 80 and overAnimalsAntineoplastic AgentsApoptosisBacillotaBacteroides fragilisCell Line, TumorColonic NeoplasmsEpithelial CellsFemaleGastrointestinal MicrobiomeHumansIleumAntineoplastic AgentsInterleukin-12OxaliplatinProgrammed Cell Death 1 ReceptorReceptors, Interleukin-1 Type I
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What OpenQuestion holds
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.