ArticleNature neuroscience2020
Assessing the depth of language processing in patients with disorders of consciousness.
Article in Nature neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 64 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
64 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Mapping fMRI research in disorders of consciousness: a bibliometric study.Frontiers in neurologyPooled it
- Effect and mechanism of repetitive transcranial magnetic stimulation of angular gyrus on patients with consciousness disorder.Frontiers in neurologyTrial
- Neural Response to Familiar Names Predicts Outcome of Comatose ICU Patients: A Prospective Observational Cohort Study.Nature communications · 2026Observational
- The Temporal Dynamics of the Labeling Algorithm During Natural Language Comprehension: Neural Evidence for Phrase Grammatical Type Generation.Neurobiology of language (Cambridge, Mass.) · 2026Article
- Neuroimaging and consciousness: applications of PET, SPECT, and advanced MRI modalities.American journal of nuclear medicine and molecular imaging · 2026Review
- Beyond computational equivalence: the behavioral inference principle for machine consciousness.Neuroscience of consciousness · 2026Review
- Article
- Characterizing consciousness states: EEG microstate dynamics in patients with disorders of consciousness during naturalistic movie-viewing.Medical & biological engineering & computing · 2025Article
- Emerging issues in the management of patients with disorders of consciousness.Journal of neurology · 2025Review
- Dynamics of EEG Microstates Change Across the Spectrum of Disorders of Consciousness.Brain topography · 2025Article
- Modulation of consciousness in disorders of consciousness by HD-tDCS targeting frontal and posterior cortical regions.Scientific reports · 2025Article
- Functional neuroimaging in disorders of consciousness: towards clinical implementation.Brain : a journal of neurology · 2025Review
- Clinical Diagnostic and Prognostic Value of Residual Language Learning Ability in Patients with Disorders of Consciousness.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Exploring cortical excitability in children with cerebral palsy through lower limb robot training based on MI-BCI.Scientific reports · 2025Article
- Reduced Modulation of Theta and Beta Oscillations Mediates Empathy Impairment in Parkinson's Disease.Brain and behavior · 2025Article
- The role of conscious attention in auditory statistical learning: Evidence from patients with impaired consciousness.iScience · 2025Article
- Leveraging meaning-induced neural dynamics to detect covert cognition via EEG during natural language listening-a case series.Frontiers in psychology · 2025Article
- Disorders of Consciousness, Language and Communication Following Severe Brain Injury.Psychologica Belgica · 2025Review
- [Applications and prospects of electroencephalography technology in neurorehabilitation assessment and treatment].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2024Review
- Revolutionizing treatment for disorders of consciousness: a multidisciplinary review of advancements in deep brain stimulation.Military Medical Research · 2024Review
4 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
16 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Assessing residual consciousness and cognitive abilities in unresponsive patients is a major clinical concern and a challenge for cognitive neuroscience. Although neuroimaging studies have demonstrated a potential for informing diagnosis and prognosis in unresponsive patients, these methods involve sophisticated brain imaging technologies, which limit their clinical application. In this study, we adopted a new language paradigm that elicited rhythmic brain responses tracking the single-word, phrase and sentence rhythms in speech, to examine whether bedside electroencephalography (EEG) recordings can help inform diagnosis and prognosis. EEG-derived neural signals, including both speech-tracking responses and temporal dynamics of global brain states, were associated with behavioral diagnosis of consciousness. Crucially, multiple EEG measures in the language paradigm were robust to predict future outcomes in individual patients. Thus, EEG-based language assessment provides a new and reliable approach to objectively characterize and predict states of consciousness and to longitudinally track individual patients' language processing abilities at the bedside.
Indexed as
Identifiers
32451482What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.