ArticleNature microbiology2020
Gangliosides are essential endosomal receptors for quasi-enveloped and naked hepatitis A virus.
Open access · greenAbstract read
In one paragraph
Article in Nature microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.
0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed
5.5field-weighted citation impact, top 3% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
45 citing papers in PubMed, 72 citations in OpenAlex.
- Host species-specific mutations in the thumb domain of the 3Dpol polymerase are required for efficient replication of human hepatitis A virus in mice.PLoS pathogens · 2026Article
- Ganglioside sialylation modulates tau internalization and pathology spread.Molecular psychiatry · 2026Article
- The low-density lipoprotein receptor LDLR mediates cellular entry of nonenveloped hepatitis A virus.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Review
- Sialic Acid-Containing Glycolipids Extend the Receptor Repertoire of Enterovirus-D68.ACS infectious diseases · 2025Article
- Heat shock protein 90 chaperone activity is required for hepatitis A virus replication.Journal of virology · 2025Article
- Noncanonical Poly(A) Polymerase TENT4 Drives Expression of Subgenomic Hepatitis A Virus RNAs in Infected Cells.Viruses · 2025Article
- Redefining the immune landscape of hepatitis A virus infection.Experimental & molecular medicine · 2025Review
- BEND6 promotes RNA viruses' replication by inhibiting innate immune responses.Science China. Life sciences · 2025Article
- Hepatovirus translation requires PDGFA-associated protein 1, an eIF4E-binding protein regulating endoplasmic reticulum stress responses.Science advances · 2024Article
- Review
- Hijacking host extracellular vesicle machinery by hepatotropic viruses: current understandings and future prospects.Journal of biomedical science · 2024Review
- A Useful Method to Provide Infectious and Cultivable In Vitro Naked Viral Particles of Hepatitis A Virus.Viruses · 2024Article
- Review
- Article
- Biochemical analysis of the host factor activity of ZCCHC14 in hepatitis A virus replication.Journal of virology · 2024Article
- Extracellular vesicle depletion and UGCG overexpression mitigate the cell density effect in HEK293 cell culture transfection.Molecular therapy. Methods & clinical development · 2024Article
- Hepatoviruses promote very-long-chain fatty acid and sphingolipid synthesis for viral RNA replication and quasi-enveloped virus release.Science advances · 2023Article
- Hepatitis A virus infection.Nature reviews. Disease primers · 2023Review
- The Battle for Survival: The Role of RNA Non-Canonical Tails in the Virus-Host Interaction.Metabolites · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
16 authors at 5 institutions in 2 countries.
Anshuman DasLineberger Comprehensive Cancer Center, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.ORCID http://orcid.org/0000-0003-2788-5315
Rodell BarrientosDepartment of Chemistry and Biochemistry, The University of North Carolina at Greensboro, Greensboro, NC, USA.
Tomoyuki ShiotaLineberger Comprehensive Cancer Center, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.ORCID http://orcid.org/0000-0001-8133-9521
Victoria MadiganDepartment of Genetics, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Ichiro MisumiDepartment of Genetics, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Kevin L McKnightLineberger Comprehensive Cancer Center, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Lu SunLineberger Comprehensive Cancer Center, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Zhucui LiUNCG Center for Translational Biomedical Research, North Carolina Research Campus, Kannapolis, NC, USA.
Rita M MeganckCurriculum in Genetics and Molecular Biology, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
You LiLineberger Comprehensive Cancer Center, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Ewelina KaluznaLineberger Comprehensive Cancer Center, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Aravind AsokanDepartment of Genetics, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Jason K WhitmireDepartment of Genetics, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.ORCID http://orcid.org/0000-0003-2578-6073
Maryna KapustinaDepartment of Cell Biology & Physiology, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Qibin ZhangDepartment of Chemistry and Biochemistry, The University of North Carolina at Greensboro, Greensboro, NC, USA.
Stanley M LemonLineberger Comprehensive Cancer Center, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. smlemon@med.unc.edu.ORCID http://orcid.org/0000-0003-1450-806X
University of North Carolina at Chapel Hill · USBroad Institute · USDavid H. Murdock Research Institute · USHenry M. Jackson Foundation · USUniversity of North Carolina at Greensboro · US
Funding
NRSA IN GENETICST32GM007092 · NIGMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI SEKELSKY, JEFF J. · 1985 to 2019
$5.9MMembrane Hijacking: Biogenesis and Fate of Quasi-Enveloped HepatovirusR01AI103083 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI LEMON, STANLEY M. · 2012 to 2021
$4.0MCritical Lipid Species in the Hepatovirus LifecycleR01AI150095 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI LEMON, STANLEY M. · 2020 to 2024
$2.6MRegulation of CD8+ T cell responses to chronic virus infectionR01AI143894 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI WHITMIRE, JASON KYLE · 2019 to 2023
$2.5MObesity associated viral pathogenesisR01AI138337 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI WHITMIRE, JASON KYLE · 2018 to 2022
$1.9MMurine Model of Human Hepatitis AR01AI131685 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI LEMON, STANLEY M., WHITMIRE, JASON KYLE · 2017 to 2021
$1.9MThe filopodial tip complex in adhesion, migration, and signalingR01GM134531 · NIGMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI CHENEY, RICHARD E · 2019 to 2022
$1.8MLipidome Remodeling During Development of T1DR01DK123499 · NIDDK · UNIVERSITY OF NORTH CAROLINA GREENSBORO · PI ZHANG, QIBIN · 2020 to 2024
$1.4MNIAID NIH HHS R01 AI103083NIAID NIH HHS R01 AI131685NIAID NIH HHS R01 AI138337NIAID NIH HHS R01 AI143894NIAID NIH HHS R01 AI150095NIDDK NIH HHS R01 DK123499NIGMS NIH HHS R01 GM134531NIGMS NIH HHS T32 GM007092
Abstract
The Picornaviridae are a diverse family of positive-strand RNA viruses that includes numerous human and veterinary pathogens
Indexed as
CapsidCapsid ProteinsCell LineEndocytosisEndosomesExosomesGangliosidesGene Knockout TechniquesGenome, ViralHeLa CellsHepatitis A virusHepatocytesHumansLysosomal-Associated Membrane Protein 1Lysosomal Membrane ProteinsLysosomesCapsid ProteinsGangliosidesLAMP1 protein, humanLysosomal-Associated Membrane Protein 1Lysosomal Membrane ProteinsNeoplasm Proteins
Identifiers
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.