ArticleMolecules and cells2020
Cucurbitacin B Activates Bitter-Sensing Gustatory Receptor Neurons via Gustatory Receptor 33a in
Article in Molecules and cells, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 16 citations in OpenAlex.
- Host Rejection of the White Mustard (Sinapis alba) by a Major Oilseed Rape Pest Is Driven by the Avoidance of Sinalbin.Journal of chemical ecology · 2026Article
- Transcriptome sequencing of Antheraea pernyi antennae for identification of olfactory-related genes.BMC genomics · 2025Article
- Cucurbitacin B and Its Derivatives: A Review of Progress in Biological Activities.Molecules (Basel, Switzerland) · 2024Review
- Genetic mutation of Tas2r104/Tas2r105/Tas2r114 cluster leads to a loss of taste perception to denatonium benzoate and cucurbitacin B.Animal models and experimental medicine · 2024Article
- Identification of candidate chemosensory genes in the antennal transcriptome of Monolepta signata.PloS one · 2024Article
- The power of Drosophila genetics in studying insect toxicology and chemical ecology.Crop health · 2023Review
- Caterpillar Responses to Gustatory Stimuli in Potato Tuber Moths: Electrophysiological and Behavioral Insights.Life (Basel, Switzerland) · 2023Article
- Acid and Alkali Taste Sensation.Metabolites · 2023Review
- Molecular Basis of Hexanoic Acid Taste inMolecules and cells · 2023Article
- Molecular sensors in the taste system of Drosophila.Genes & genomics · 2023Review
- Protocol for binary food choice assays usingSTAR protocols · 2022Article
- Human Endogenous Retroviruses as Gene Expression Regulators: Insights from Animal Models into Human Diseases.Molecules and cells · 2021Review
- Ionotropic receptors mediate nitrogenous waste avoidance in Drosophila melanogaster.Communications biology · 2021Article
- Cucurbitacin B Suppresses Hyperglycemia Associated with a High Sugar Diet and Promotes Sleep inMolecules and cells · 2021Article
- Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The Gustatory system enables animals to detect toxic bitter chemicals, which is critical for insects to survive food induced toxicity. Cucurbitacin is widely present in plants such as cucumber and gourds that acts as an anti-herbivore chemical and an insecticide. Cucurbitacin has a harmful effect on insect larvae as well. Although various beneficial effects of cucurbitacin such as alleviating hyperglycemia have also been documented, it is not clear what kinds of molecular sensors are required to detect cucurbitacin in nature. Cucurbitacin B, a major bitter component of bitter melon, was applied to induce action potentials from sensilla of a mouth part of the fly, labellum. Here we identify that only
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.