Evidence map›Paper›PMID 32450945›Full record

SynthesisEuropean psychiatry : the journal of the Association of European Psychiatrists2020

Symptom trajectories into eating disorders: A systematic review of longitudinal, nonclinical studies in children/adolescents.

Jessica McClelland, Lauren Robinson, Rachel Potterton, Victoria Mountford, Ulrike Schmidt

Abstract readSystematic Review
In one paragraph

Synthesis in European psychiatry : the journal of the Association of European Psychiatrists, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Social Anxiety and Peer Relationships Predict Weight Recovery in Adolescent Onset Anorexia Nervosa.European eating disorders review : the journal of the Eating Disorders Association · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. GDF15 Is Elevated in Eating Disorders and Is Involved in the Gut-Brain Axis via Ghrelin.European eating disorders review : the journal of the Eating Disorders Association · 2026
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Nature and nurture in fussy eating from toddlerhood to early adolescence: findings from the Gemini twin cohort.Journal of child psychology and psychiatry, and allied disciplines · 2025
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jessica McClellandSouth London and Maudsley NHS Foundation Trust, London, United Kingdom.ORCID 0000-0002-2030-084X
Lauren RobinsonInstitute of Psychiatry, Psychology and Neuroscience, King's College London, London, United Kingdom.
Rachel PottertonInstitute of Psychiatry, Psychology and Neuroscience, King's College London, London, United Kingdom.ORCID 0000-0002-4323-4814
Victoria MountfordSouth London and Maudsley NHS Foundation Trust, London, United Kingdom.
Ulrike SchmidtSouth London and Maudsley NHS Foundation Trust, London, United Kingdom.

Funding

Medical Research Council MC_PC_15018Medical Research Council MC_PC_19009
6 · The paper itself

Abstract

backgroundEating disorders (EDs) are serious mental illnesses that can be life-threatening. Stage of illness models and early intervention strategies could be informed by a better understanding of symptomatology that precedes the onset of an ED. This review aims to explore which symptoms (both ED and other psychiatric disorder-related) exist prior to the onset of an ED and whether there any prospective associations between these symptomatologies.

methodsA systematic literature review was conducted in MEDLINE, Embase, and PsycINFO for large, longitudinal, prospective studies in nonclinical cohorts of children/adolescents that report symptoms prior to the onset of an ED. A quality assessment of included studies was conducted using the Newcastle-Ottawa Quality Assessment Scale.

resultsA total of 22 studies were included, and over half were assessed to be of good quality. Studies identified the presence of a broad range of ED and other psychiatric disorder-related symptoms prior to ED onset. Possible prospective associations were identified, including early eating and feeding difficulties in childhood, to ED-related symptoms (e.g., dieting and body dissatisfaction) and other psychiatric disorder-related symptoms (e.g., anxiety and depression) in childhood/early adolescence, progressing to severe symptomatology (e.g., extreme weight control behaviors and self-harm) in mid-adolescence/emerging adulthood.

conclusionThe trajectory of symptoms identified to precede and possibly predict onset of an ED may inform early intervention strategies within the community. Suggestions for further research are provided to establish these findings and the clinical implications of these discussed, in order to inform how best to target prodromal stages of EDs.

Indexed as

Adolescent DevelopmentAdolescentAdolescent BehaviorAdultAnxiety DisordersChildComorbidityDisease ProgressionFeeding and Eating DisordersFemaleHumansLongitudinal StudiesMaleProspective StudiesRisk FactorsChild and adolescent psychiatrycomorbidityearly interventioneating disorderpsychiatric symptoms

Identifiers

PMID32450945
PMCPMC7355161

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.