Evidence map›Paper›PMID 32450916›Full record

ArticleInfectious diseases of poverty2020

Tuberculosis infection prevention and control: why we need a whole systems approach.

Karina Kielmann, Aaron S Karat, Gimenne Zwama, Christopher Colvin, Alison Swartz, Anna S Voce, Tom A Yates, Hayley MacGregor, Nicky McCreesh, Idriss Kallon and 4 more

Abstract read
In one paragraph

Article in Infectious diseases of poverty, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

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  17. Occupational Risk of AirborneInternational journal of environmental research and public health · 2021
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Karina KielmannThe Institute for Global Health and Development, Queen Margaret University, Edinburgh, EH21 6UU, UK. kkielmann@qmu.ac.uk.ORCID http://orcid.org/0000-0001-5519-1658
Aaron S KaratThe Institute for Global Health and Development, Queen Margaret University, Edinburgh, EH21 6UU, UK.
Gimenne ZwamaThe Institute for Global Health and Development, Queen Margaret University, Edinburgh, EH21 6UU, UK.
Christopher ColvinDivision of Social and Behavioural Sciences, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.
Alison SwartzDivision of Social and Behavioural Sciences, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.
Anna S VoceDiscipline Public Health Medicine, School of Nursing and Public Health, University of KwaZulu-Natal, Durban, South Africa.
Tom A YatesDepartment of Infectious Disease, Faculty of Medicine, Imperial College London, London, UK.
Hayley MacGregorThe Institute of Development Studies, University of Sussex, Brighton, UK.
Nicky McCreeshTB Centre, London School of Hygiene & Tropical Medicine, London, UK.
Idriss KallonDivision of Social and Behavioural Sciences, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.
Anna VassallTB Centre, London School of Hygiene & Tropical Medicine, London, UK.
Indira GovenderTB Centre, London School of Hygiene & Tropical Medicine, London, UK.
Janet SeeleyDepartment of Global Health and Development, Faculty of Public Health and Policy, London School of Hygiene & Tropical Medicine, London, UK.
Alison D GrantTB Centre, London School of Hygiene & Tropical Medicine, London, UK.

Funding

Medical Research Council MR/M002675/1Medical Research Council MR/P002404/1
6 · The paper itself

Abstract

Infection prevention and control (IPC) measures to reduce transmission of drug-resistant and drug-sensitive tuberculosis (TB) in health facilities are well described but poorly implemented. The implementation of TB IPC has been assessed primarily through quantitative and structured approaches that treat administrative, environmental, and personal protective measures as discrete entities. We present an on-going project entitled Umoya omuhle ("good air"), conducted in two provinces of South Africa, that adopts an interdisciplinary, 'whole systems' approach to problem analysis and intervention development for reducing nosocomial transmission of Mycobacterium tuberculosis (Mtb) through improved IPC. We suggest that TB IPC represents a complex intervention that is delivered within a dynamic context shaped by policy guidelines, health facility space, infrastructure, organisation of care, and management culture. Methods drawn from epidemiology, anthropology, and health policy and systems research enable rich contextual analysis of how nosocomial Mtb transmission occurs, as well as opportunities to address the problem holistically. A 'whole systems' approach can identify leverage points within the health facility infrastructure and organisation of care that can inform the design of interventions to reduce the risk of nosocomial Mtb transmission.

Indexed as

HumansInfection ControlMycobacterium tuberculosisPrimary PreventionSouth AfricaSystems AnalysisTuberculosisDrug-resistant tuberculosisHealth systemInfection prevention and controlSouth Africa

Identifiers

PMID32450916
PMCPMC7249303

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.