ArticleBMC medicine2020
Children's microvascular traits and ambient air pollution exposure during pregnancy and early childhood: prospective evidence to elucidate the developmental origin of particle-induced disease.
Article in BMC medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed, 16 citations in OpenAlex.
- The association between preschoolers' retinal microcirculation and the indoor microbial environment: results of the ENVIRONAGE birth cohort.Scientific reports · 2025Article
- Newborn glomerular function and gestational particulate air pollution.EBioMedicine · 2024Article
- Increased vascular stiffness in children exposed in utero but not children exposed postnatally to emissions from a coal mine fire.Environmental epidemiology (Philadelphia, Pa.) · 2024Article
- A Long Way from Steubenville: Environmental Epidemiology in a Rapidly Changing World.American journal of epidemiology · 2023Article
- Wildland fire, air pollution and cardiovascular health: is it time to focus on the microvasculature as a risk assessment tool?Frontiers in physiology · 2023Review
- Adverse Effects of Black Carbon (BC) Exposure during Pregnancy on Maternal and Fetal Health: A Contemporary Review.Toxics · 2022Review
- Health Outcomes in Children Associated with Prenatal and Early-Life Exposures to Air Pollution: A Narrative Review.Toxics · 2022Review
- Article
- 'Fetal side' of the placenta: anatomical mis-annotation of carbon particle 'transfer' across the human placenta.Nature communications · 2021Article
- Air pollution and retinal vessel diameter and blood pressure in school-aged children in a region impacted by residential biomass burning.Scientific reports · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors at 5 institutions in 1 country.
Funding
Abstract
backgroundParticulate matter exposure during in utero life may entail adverse health outcomes later in life. The microvasculature undergoes extensive, organ-specific prenatal maturation. A growing body of evidence shows that cardiovascular disease in adulthood is rooted in a dysfunctional fetal and perinatal development, in particular that of the microcirculation. We investigate whether prenatal or postnatal exposure to PM
methodsWe measured the retinal microvascular diameters, the central retinal arteriolar equivalent (CRAE) and central retinal venular equivalent (CRVE), and the vessel curvature by means of the tortuosity index (TI) in young children (mean [SD] age 4.6 [0.4] years), followed longitudinally within the ENVIRONAGE birth cohort. We modeled daily prenatal and postnatal PM
resultsAn interquartile range (IQR) increase in PM
conclusionsOur results link prenatal and postnatal air pollution exposure with changes in a child's microvascular traits as a fundamental novel mechanism to explain the developmental origin of cardiovascular disease.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.