ArticleBMC veterinary research2020
Clinical signs, MRI findings and outcome in dogs with peripheral vestibular disease: a retrospective study.
Article in BMC veterinary research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Idiopathic facial neuropathy in cats: clinical presentation, magnetic resonance imaging findings, and outcome.Journal of veterinary internal medicine · 2026Article
- Ocular Manifestations in Dogs With Facial Nerve Dysfunction.Veterinary ophthalmology · 2026Article
- Prevalence of incidental and causative otitis in 380 client-owned dogs undergoing brain magnetic resonance imaging for signs of vestibular and non-vestibular disease.Journal of veterinary internal medicine · 2026Article
- Case Report: Recurrent vestibular episodes in a dog resembling Meniere's disease.Frontiers in veterinary science · 2026Article
- Peripheral vestibular syndrome in cats: Clinical presentation, diagnostic findings and outcome in 196 cases.The Veterinary record · 2025Article
- Feline atopic syndrome: An insight into its effects on the central nervous system through vestibular disease.The Canadian veterinary journal = La revue veterinaire canadienne · 2025Article
- Common Neurologic Diseases in Geriatric Dogs.Animals : an open access journal from MDPI · 2024Review
- Short- and long-term outcomes of subtotal ear canal ablation and lateral bulla osteotomy in French bulldogs.Canadian journal of veterinary research = Revue canadienne de recherche veterinaire · 2023Article
- Current definition, diagnosis, and treatment of canine and feline idiopathic vestibular syndrome.Frontiers in veterinary science · 2023Article
- Otitis media and interna with or without polyps in cats: association between meningeal enhancement on postcontrast MRI, cerebrospinal fluid abnormalities, and clinician treatment choice and outcome.Journal of feline medicine and surgery · 2022Article
- Ondansetron in dogs with nausea associated with vestibular disease: A double-blinded, randomized placebo-controlled crossover study.Journal of veterinary internal medicine · 2022Article
- The use of ondansetron for the treatment of nausea in dogs with vestibular syndrome.BMC veterinary research · 2021Article
- Clinical features and outcome of 10 dogs with suspected idiopathic vestibular epilepsy.Journal of veterinary internal medicineArticle
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Authors and funding
7 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundVestibular dysfunction is relatively common in dogs, with a prevalence of 0.08% reported in primary veterinary care in the UK. There are several studies investigating how to differentiate between peripheral and central vestibular disease but only limited information regarding the possible underlying causes for peripheral vestibular dysfunction in dogs. This study therefore aimed to describe the clinical signs, magnetic resonance imaging findings (MRI), underlying causes and outcome in a large population of dogs diagnosed with peripheral vestibular disease.
resultsOne hundred eighty-eight patients were included in the study with a median age of 6.9 years (range 3 months to 14.6 years). Neurological abnormalities included head tilt (n = 185), ataxia (n = 123), facial paralysis (n = 103), nystagmus (n = 97), positional strabismus (n = 93) and Horner syndrome (n = 7). The most prevalent diagnosis was idiopathic vestibular disease (n = 128), followed by otitis media and/or interna (n = 49), hypothyroidism (n = 7), suspected congenital vestibular disease (n = 2), neoplasia (n = 1) and cholesteatoma (n = 1). Long-term follow-up revealed persistence of head tilt (n = 50), facial paresis (n = 41) and ataxia (n = 6) in some cases. Recurrence of clinical signs was observed in 26 dogs. Increasing age was associated with a mild increased chance of diagnosis of idiopathic vestibular syndrome rather than otitis media and/or interna (P = 0.022, OR = 0.866; CI 0.765-0.980). History of previous vestibular episodes (P = 0.017, OR = 3.533; CI 1.251-9.981) was associated with an increased likelihood of resolution of the clinical signs whilst contrast enhancement of cranial nerves VII and/or VIII on MRI (P = 0.018, OR = 0.432; CI 0.251-0.868) was associated with a decreased chance of resolution of the clinical signs.
conclusionsIdiopathic vestibular disease is the most common cause of peripheral vestibular dysfunction in dogs and it is associated with advanced age. Incomplete recovery from peripheral vestibular disease is common, especially in dogs presenting with cranial nerve enhancement on MRI but less so if there is previous history of vestibular episodes.
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