Evidence map›Paper›PMID 32450733›Full record

Trial reportOtolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery2020

Surgical Field Visualization during Functional Endoscopic Sinus Surgery: Comparison of Propofol- vs Desflurane-Based Anesthesia.

Suneeta Gollapudy, Drake A Gashkoff, David M Poetker, Todd A Loehrl, Matthias L Riess

Open access · greenAbstract readComparative StudyRandomized Controlled Trial
In one paragraph

Trial report in Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Does preoperative administration of hypotensive agents affect the quality of the surgical field during endoscopic sinus surgery? A triple-blind randomized controlled trial.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2023
    Trial
  3. Trial
  4. Article
  5. Article
  6. Article
  7. The Devil Is in the Detail.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2021
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Suneeta GollapudyDepartment of Anesthesiology, Medical College of Wisconsin, Milwaukee, Wisconsin, USA.
Drake A GashkoffMedical School, Medical College of Wisconsin, Milwaukee, Wisconsin, USA.
David M PoetkerDepartment of Otolaryngology and Communication Sciences, Medical College of Wisconsin, Milwaukee, Wisconsin, USA.
Todd A LoehrlDepartment of Otolaryngology and Communication Sciences, Medical College of Wisconsin, Milwaukee, Wisconsin, USA.
Matthias L RiessAnesthesiology, TVHS VA Medical Center, Nashville, Tennessee, USA.
Medical College of Wisconsin · USMilwaukee VA Medical Center · USVanderbilt University Medical Center · US

Funding

Reperfusion Injury Protection Strategies During Basic Life SupportR01HL123227 · NHLBI · UNIVERSITY OF MINNESOTA · PI YANNOPOULOS, DEMETRIS · 2013 to 2017
$5.1M
Novel Copolymer-based Cell Membrane Stabilizers to Attenuate Myocardial InfarctionI01BX003482 · VA · VETERANS HEALTH ADMINISTRATION · PI RIESS, MATTHIAS L. · 2018 to 2022
–
BLRD VA I01 BX003482BLRD VA IK2 BX001278NHLBI NIH HHS R01 HL123227
6 · The paper itself

Abstract

objectiveTo assess if the type of general anesthetic affects bleeding and field visualization during endoscopic sinus surgery. STUDY

designProspective, randomized, controlled trial.

settingAcademic teaching hospital and Veterans Affairs hospital in the United States. SUBJECTS AND

methodsSeventy patients were randomized to 1 of 3 anesthetic regimens: (1) the volatile anesthetic desflurane (n = 22), (2) intravenous anesthesia with propofol (n = 25), or (3) a combination of propofol and desflurane (n = 23). Intravenous remifentanil was titrated to decrease the mean arterial pressure to 60 to 70 mm Hg but not ≥30% from baseline. Surgical bleeding scores were recorded along with bleeding rates and hemodynamic parameters, including cardiac output and systemic vascular resistance through pulse contour analysis from a radial arterial line. Statistics: multiple comparison tests and regression analyses; α = .05.

resultsThere were no differences in bleeding rate (median, 0.58, 0.85, 0.57 mL min

conclusionWhen remifentanil is used for controlled hypotension, propofol has no advantage over desflurane to improve surgical field visualization during functional endoscopic sinus surgery.

Indexed as

Anesthetics, GeneralDesfluranePropofolAdultAnalgesics, OpioidBlood Loss, SurgicalBlood PressureEndoscopyFemaleHumansMaleMiddle AgedRemifentanilSinusitisAnalgesics, OpioidAnesthetics, GeneralDesfluranePropofolRemifentanilcardiac outputFloTracremifentanilTIVAvolatile anesthetics

Identifiers

PMID32450733
PMCPMC8500338
OpenAlexW3031141835

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.