ArticleJournal of the American Chemical Society2020
Enantioselective Hydroxylation of Benzylic C(sp
Article in Journal of the American Chemical Society, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed.
- Bioorthogonal Gold-Catalyzed Hydrothiolation Leading to Amide Bond Cleavage of Ethynylated Biarylbutanamide Precursors.Journal of the American Chemical Society · 2026Article
- Bio-Inspired Photocatalytic Degradation of Humic Acids over TiOBiomimetics (Basel, Switzerland) · 2026Article
- Electrochemical Direct Benzylic C-H Hydroxylation with HCommunications chemistry · 2026Article
- Article
- Ultrasensitive and long-lasting bioluminescence immunoassay for point-of-care viral antigen detection.Nature biomedical engineering · 2025Article
- Hooked for Decay with Hydrophobic-Coated Magnetic Beads to Grapple and Disintegrate Nanoplastics.Angewandte Chemie (International ed. in English) · 2025Article
- A fully automated, ultrasensitive luminescence cascade sensor to address hepatitis C diagnostic disparity.Innovation (Cambridge (Mass.)) · 2025Article
- Understanding Catalytic Enantioselective C-H Bond Oxidation at Nonactivated Methylenes Through Predictive Statistical Modeling Analysis.ACS catalysis · 2025Article
- Aggregation-Driven Photoinduced α-C(spJournal of the American Chemical Society · 2024Article
- Spiers Memorial Lecture: Shielding the active site: a streptavidin superoxide-dismutase chimera as a host protein for asymmetric transfer hydrogenation.Faraday discussions · 2023Article
- C-H Bonds as Functional Groups: Simultaneous Generation of Multiple Stereocenters by Enantioselective Hydroxylation at Unactivated Tertiary C-H Bonds.Journal of the American Chemical Society · 2023Article
- A Horseradish Peroxidase-Mediator System for Benzylic C-H Activation.ACS catalysis · 2022Article
- Designing Artificial Metalloenzymes by Tuning of the Environment beyond the Primary Coordination Sphere.Chemical reviews · 2022Review
- Review
- Synthetic prodrug design enables biocatalytic activation in mice to elicit tumor growth suppression.Nature communications · 2022Article
- C-H Bond Cleavage by Bioinspired Nonheme Metal Complexes.Inorganic chemistry · 2021Review
- Artificial Metalloproteins with Dinuclear Iron-Hydroxido Centers.Journal of the American Chemical Society · 2021Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The selective hydroxylation of C-H bonds is of great interest to the synthetic community. Both homogeneous catalysts and enzymes offer complementary means to tackle this challenge. Herein, we show that biotinylated Fe(TAML)-complexes (TAML = Tetra Amido Macrocyclic Ligand) can be used as cofactors for incorporation into streptavidin to assemble artificial hydroxylases. Chemo-genetic optimization of both cofactor and streptavidin allowed optimizing the performance of the hydroxylase. Using H
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Registered trials
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