Evidence map›Paper›PMID 32450520›Full record

ArticleiScience2020

Controlled Transdermal Release of Antioxidant Ferulate by a Porous Sc(III) MOF.

Génesis Osorio-Toribio, Miriam de J Velásquez-Hernández, Paulo G M Mileo, J Antonio Zárate, Javier Aguila-Rosas, Gerardo Leyva-Gómez, Roberto Sánchez-Sánchez, Jonathan J Magaña, Mario Alberto Pérez-Díaz, Isabel Abánades Lázaro and 4 more

Abstract read
In one paragraph

Article in iScience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Gas Delivery Relevant to Human Health using Porous Materials.Chemistry (Weinheim an der Bergstrasse, Germany) · 2024
    Review
  6. Article
  7. Review
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Génesis Osorio-ToribioLaboratorio de Fisicoquímica y Reactividad de Superficies (LaFReS), Instituto de Investigaciones en Materiales, Universidad Nacional Autónoma de México, Ciudad de México, Mexico.
Miriam de J Velásquez-HernándezInstitute of Physical and Theoretical Chemistry, Graz University of Technology, Stremayrgasse 9, 8010 Graz, Austria.
Paulo G M MileoICGM, Univ. Montpellier, CNRS, ENSCM, Montpellier, France.
J Antonio ZárateLaboratorio de Fisicoquímica y Reactividad de Superficies (LaFReS), Instituto de Investigaciones en Materiales, Universidad Nacional Autónoma de México, Ciudad de México, Mexico; ICGM, Univ. Montpellier, CNRS, ENSCM, Montpellier, France.
Javier Aguila-RosasLaboratorio de Fisicoquímica y Reactividad de Superficies (LaFReS), Instituto de Investigaciones en Materiales, Universidad Nacional Autónoma de México, Ciudad de México, Mexico; Departamento de Sistemas Biológicos, Universidad Autónoma Metropolitana-Azcapotzalco, Ciudad de México, Mexico.
Gerardo Leyva-GómezDepartamento de Farmacia, Facultad de Química, Universidad Nacional Autónoma de México, Ciudad de México, México.
Roberto Sánchez-SánchezUnidad de Ingeniería de Tejidos Terapia Celular y Medicina Regenerativa Instituto Nacional de Rehabilitación Luis Guillermo Ibarra Ibarra (INR-LGII), Ciudad de México, Mexico.
Jonathan J MagañaLaboratorio de Medicina Genómica, Instituto Nacional de Rehabilitación Luis Guillermo Ibarra Ibarra (INR-LGII), Ciudad de México, Mexico.
Mario Alberto Pérez-DíazLaboratorio de Biomembranas, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, Ciudad de México, Mexico.
Isabel Abánades LázaroUniversidad de Valencia (ICMol), Catedrático José Beltrán-2, Paterna, Spain; WestCHEM School of Chemistry, University of Glasgow, Joseph Black Building, University Avenue, Glasgow G12 8QQ, UK.
Ross S ForganWestCHEM School of Chemistry, University of Glasgow, Joseph Black Building, University Avenue, Glasgow G12 8QQ, UK.
Guillaume MaurinICGM, Univ. Montpellier, CNRS, ENSCM, Montpellier, France. Electronic address: guillaume.maurin1@umontpellier.fr.
Enrique LimaLaboratorio de Fisicoquímica y Reactividad de Superficies (LaFReS), Instituto de Investigaciones en Materiales, Universidad Nacional Autónoma de México, Ciudad de México, Mexico. Electronic address: lima@iim.unam.mx.
Ilich A IbarraLaboratorio de Fisicoquímica y Reactividad de Superficies (LaFReS), Instituto de Investigaciones en Materiales, Universidad Nacional Autónoma de México, Ciudad de México, Mexico. Electronic address: argel@unam.mx.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Sc(III) MOF-type MFM-300(Sc) is demonstrated in this study to be stable under physiological conditions (PBS), biocompatible (to human skin cells), and an efficient drug carrier for the long-term controlled release (through human skin) of antioxidant ferulate. MFM-300(Sc) also preserves the antioxidant pharmacological effects of ferulate while enhancing the bio-preservation of dermal skin fibroblasts, during the delivery process. These discoveries pave the way toward the extended use of Sc(III)-based MOFs as drug delivery systems (DDSs).

Indexed as

ChemistryInorganic ChemistryMaterials StructureMedicine

Identifiers

PMID32450520
PMCPMC7251947

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.