Evidence map›Paper›PMID 32450470›Full record

ReviewBreast (Edinburgh, Scotland)2020

A multi-stakeholder approach in optimising patients' needs in the benefit assessment process of new metastatic breast cancer treatments.

Fatima Cardoso, Nils Wilking, Renato Bernardini, Laura Biganzoli, Jaime Espin, Kaisa Miikkulainen, Susanne Schuurman, Danielle Spence, Sabine Spitz, Sonia Ujupan and 2 more

Abstract readReview
In one paragraph

Review in Breast (Edinburgh, Scotland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Fatima CardosoChampalimaud Clinical Centre, Champalimaud Foundation and ABC Global Alliance, Lisbon, Portugal. Electronic address: fatimacardoso@fundacaochampalimaud.pt.
Nils WilkingKarolinska Institutet, Stockholm, Sweden.
Renato BernardiniUniversity of Catania Medical School, Catania, Italy.
Laura BiganzoliHospital of Prato and European Society of Breast Cancer Specialists, Florence, Italy.
Jaime EspinAndalusian School of Public Health, Escuela Andaluza de Salud Pública (EASP), Granada, Spain; CIBER en Epidemiología y Salud Pública / CIBER of Epidemiology and Public Health (CIBERESP), Spain; Instituto de Investigación Biosanitaria ibs, Granada, Spain.
Kaisa MiikkulainenICON Plc, Stockholm, Sweden.
Susanne SchuurmanICON Plc, Stockholm, Sweden at the time of article submission.
Danielle SpenceBreast Cancer Network Australia, Australia.
Sabine SpitzEuropa Donna, Vienna, Austria and European Patients' Academy on Therapeutic Innovation (EUPATI).
Sonia UjupanEli Lilly and Company, Brussels, Belgium.
Nicole ZernikEuropa Donna, Paris, France.
Jenn GordonCanadian Breast Cancer Network, Ottawa, ON, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is a growing understanding as science evolves that different cancer types require different approaches to treatment evaluation, especially in the metastatic stages. The introduction of new metastatic breast cancer (MBC) treatments may be hindered by several elements, including the availability of relevant evidence related to disease-specific outcomes, the benefit assessment process around the evaluation of the clinical benefit and the patients' need of new treatments. The Steering Committee (SC) found that not all issues relevant to MBC patients are consistently considered in the current benefit assessment process of new treatments. Among these are overall survival, time-to-event endpoints (e.g. progression-free survival), patients' priorities, burden of disease, MBC-specific quality of life, value in delaying chemotherapy, route of administration, side effects and toxicities, treatment adherence and the benefit of real-world evidence. This paper calls on decision makers to (1) Include MBC-specific patient priorities and outcomes in the overall benefit assessments of new MBC treatments; (2) Enhance multi-stakeholder collaboration in order to improve MBC patient outcomes.

Indexed as

Stakeholder ParticipationBreast NeoplasmsDecision MakingHealth PlanningHumansPatient PreferencePolicyQuality of LifeTechnology Assessment, BiomedicalHealth technology assessmentMetastatic breast cancerPatient preferencesPolicyStakeholdersTreatment benefit

Identifiers

PMID32450470
PMCPMC7487948

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.