Evidence map›Paper›PMID 32450087›Full record

ArticleThe Journal of allergy and clinical immunology2020

ACE2, TMPRSS2, and furin gene expression in the airways of people with asthma-implications for COVID-19.

Peter Bradding, Matthew Richardson, Timothy S C Hinks, Peter H Howarth, David F Choy, Joseph R Arron, Sally E Wenzel, Salman Siddiqui

Open access · hybridAbstract readComment
In one paragraph

Article in The Journal of allergy and clinical immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed, 1 pooled it
11.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

56 citing papers in PubMed, 1 synthesis or guideline pooled it, 104 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Susceptibility of Patients with Airway Disease to SARS-CoV-2 Infection.American journal of respiratory and critical care medicine · 2022
    Article
  12. Review
  13. Article
  14. Expression ofAmerican journal of respiratory cell and molecular biology · 2022
    Article
  15. Chronic Rhinosinusitis and COVID-19.The journal of allergy and clinical immunology. In practice · 2022
    Review
  16. Article
  17. Article
  18. Article
  19. Review
  20. Asthma and COVID-19: an update.European respiratory review : an official journal of the European Respiratory Society · 2021
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Peter BraddingNational Institute for Health Research (NIHR) Leicester Biomedical Research Centre (Respiratory theme) and College of Life Sciences, University of Leicester, Leicester, United Kingdom. Electronic address: pb46@le.ac.uk.
Matthew RichardsonNational Institute for Health Research (NIHR) Leicester Biomedical Research Centre (Respiratory theme) and College of Life Sciences, University of Leicester, Leicester, United Kingdom.
Timothy S C HinksRespiratory Medicine Unit and National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), Nuffield Department of Medicine Experimental Medicine, University of Oxford, Oxford, United Kingdom.
Peter H HowarthClinical and Experimental Science, Faculty of Medicine, University of Southampton and National Institute for Health Research (NIHR) Southampton Biomedical Research Centre, University Hospital Southampton NHS Foundation Trust, Southampton, United Kingdom.
David F ChoyGenentech, South San Francisco, Calif.
Joseph R ArronGenentech, South San Francisco, Calif.
Sally E WenzelUniversity of Pittsburgh Asthma Institute at UPMC/UPSOM, Pittsburgh, Pa.
Salman SiddiquiNational Institute for Health Research (NIHR) Leicester Biomedical Research Centre (Respiratory theme) and College of Life Sciences, University of Leicester, Leicester, United Kingdom.
University of Leicester · GBNational Institute for Health Research · GBNIHR Southampton Biomedical Research Centre · GBUniversity of Oxford · GBUniversity of Pittsburgh · US

Funding

Wellcome Trust
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AsthmaCoronavirus InfectionsFurinPandemicsPneumonia, ViralAdultBetacoronavirusChinaCOVID-19HumansInpatientsPeptidyl-Dipeptidase ARetrospective StudiesRisk FactorsSARS-CoV-2FurinPeptidyl-Dipeptidase A

Identifiers

PMID32450087
PMCPMC7243787
OpenAlexW3027047557

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.