ArticleRNA biology2020
Discovery of new group I-D introns leads to creation of subtypes and link to an adaptive response of the mitochondrial genome in fungi.
Article in RNA biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 22 citations in OpenAlex.
- The Viruses ofViruses · 2025Article
- Comparative Mitogenome Analysis ofJournal of fungi (Basel, Switzerland) · 2025Article
- Baseline Sensitivity of Botryosphaeria spp. Isolated from Apples to Pyraclostrobin in Korea.The plant pathology journal · 2025Article
- Characterization of the mitochondrial genomes forIMA fungus · 2025Article
- Complete mitochondrial genome sequence of the white root rot pathogenMitochondrial DNA. Part B, Resources · 2024Article
- Group I introns: Structure, splicing and their applications in medical mycology.Genetics and molecular biology · 2024Article
- Group I Intron as a Potential Target for Antifungal Compounds: Development of aMolecules (Basel, Switzerland) · 2023Article
- Mitogenomics and mitochondrial gene phylogeny decipher the evolution of Saccharomycotina yeasts.Genome biology and evolution · 2022Article
- Editorial: Mitochondrial Genomes and Mitochondrion Related Gene Insights to Fungal Evolution.Frontiers in microbiology · 2022Article
- Refining Mitochondrial Intron Classification With ERPIN: Identification Based on Conservation of Sequence Plus Secondary Structure Motifs.Frontiers in microbiology · 2022Article
- Comparative analysis of Malassezia furfur mitogenomes and the development of a mitochondria-based typing approach.FEMS yeast research · 2021Article
- Organellar Introns in Fungi, Algae, and Plants.Cells · 2021Review
- Mitochondrial Genomics of Six Cacao Pathogens From the Basidiomycete FamilyFrontiers in microbiology · 2021Article
- The Mitogenomes ofFrontiers in microbiology · 2021Article
- Editorial: The Significance of Mitogenomics in Mycology.Frontiers in microbiology · 2020Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Group I catalytic introns are widespread in bacterial, archaeal, viral, organellar, and some eukaryotic genomes, where they are reported to provide regulatory functions. The group I introns are currently divided into five types (A-E), which are themselves distributed into several subtypes, with the exception of group I type D intron (GI-D). GI-D introns belong to the rarest group with only 17 described to date, including only one with a putative role reported in fungi, where it would interfere with an adaptive response in the cytochrome b (COB) gene to quinone outside inhibitor (QoI) fungicide resistance. Using homology search methods taking into account both conserved sequences and RNA secondary structures, we analysed the mitochondrial genomes or COB genes of 169 fungal species, including some frequently under QoI selection pressure. These analyses have led to the identification of 216 novel GI-D introns, and the definition of three distinct subtypes, one of which being linked with a functional activity. We have further uncovered a homing site for this GI-D intron type, which helps refine the accepted model of quinone outside inhibitor resistance, whereby mobility of the intron across fungal mitochondrial genomes, would influence a fungus ability to develop resistance to QoIs.
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