Evidence map›Paper›PMID 32449433›Full record

ReviewRNA biology2020

LncRNAs as tumor cell intrinsic factors that affect cancer immunotherapy.

Sergey D Egranov, Qingsong Hu, Chunru Lin, Liuqing Yang

Open access · bronzeAbstract readReview
In one paragraph

Review in RNA biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.9field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Sergey D EgranovDepartment of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center , Houston, TX, USA.
Qingsong HuDepartment of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center , Houston, TX, USA.
Chunru LinDepartment of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center , Houston, TX, USA.
Liuqing YangDepartment of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center , Houston, TX, USA.
The University of Texas MD Anderson Cancer Center · US

Funding

Long Noncoding RNA Advocates Immune Resistant MicroenvironmentR01CA231011 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI LIN, CHUNRU · 2019 to 2023
$2.9M
Combinatorial Treatment Strategies to Counteract EGFR ResistanceR01CA218036 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI YANG, LIUQING · 2017 to 2021
$1.8M
Significance of Inhibiting Long Non-coding RNAs in Advanced Breast CancerR01CA218025 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI LIN, CHUNRU · 2017 to 2020
$1.5M
NCI NIH HHS R01 CA218025NCI NIH HHS R01 CA218036NCI NIH HHS R01 CA231011
6 · The paper itself

Abstract

Long noncoding RNAs (lncRNAs) have been found to associate with all major types of malignancies and play important roles in regulating several hallmarks of cancer by interacting with proteins, DNA, and RNA. The possible functions of lncRNAs and their roles in the regulation of tumour growth will be reported and discussed in the present review. In our recent report, based on genetic mice models and a series of systematic analyses, we suggested that lncRNAs also play critical roles in the regulation of antigen presentation in tumour cells and allow tumour cells to escape immune surveillance, which further broadens the scope of understanding lncRNA functions and how they relate to cancer immunotherapy resistance.

Indexed as

Gene Expression Regulation, NeoplasticImmunotherapyAnimalsAntigen PresentationBiomarkers, TumorDisease ManagementDisease Models, AnimalDisease SusceptibilityHumansNeoplasmsRNA, Long NoncodingBiomarkers, TumorLINK-A long non-coding RNA, humanRNA, Long Noncodingantigen presentationCancer immunologyLong noncoding RNAtumour intrinsic factor

Identifiers

PMID32449433
PMCPMC7567504
OpenAlexW3026111068

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.