Evidence map›Paper›PMID 32449140›Full record

ArticleVirus genes2020

The characteristics and genome analysis of vB_ApiP_XC38, a novel phage infecting Acinetobacter pittii.

Mengjun Cheng, Man Luo, Hengyu Xi, Yunze Zhao, Shuai Le, Li-Kuang Chen, Demeng Tan, Yuan Guan, Tianqi Wang, Wenyu Han and 3 more

Abstract read
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In one paragraph

Article in Virus genes, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Lytic Capsule-SpecificViruses · 2024
    Article
  3. Article
  4. Potential Usefulness of Bacteriophages for the Treatment of Multidrug-ResistantThe Malaysian journal of medical sciences : MJMS · 2023
    Review
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Mengjun ChengShanghai Institute of Phage, Shanghai Public Health Clinical Center, Fudan University, Shanghai, 201508, China.
Man LuoKey Laboratory of Zoonosis Research, Ministry of Education, College of Veterinary Medicine, Jilin University, Changchun, 130062, China.
Hengyu XiKey Laboratory of Zoonosis Research, Ministry of Education, College of Veterinary Medicine, Jilin University, Changchun, 130062, China.
Yunze ZhaoShanghai Institute of Phage, Shanghai Public Health Clinical Center, Fudan University, Shanghai, 201508, China.
Shuai LeShanghai Institute of Phage, Shanghai Public Health Clinical Center, Fudan University, Shanghai, 201508, China.
Li-Kuang ChenShanghai Institute of Phage, Shanghai Public Health Clinical Center, Fudan University, Shanghai, 201508, China.
Demeng TanShanghai Institute of Phage, Shanghai Public Health Clinical Center, Fudan University, Shanghai, 201508, China.
Yuan GuanKey Laboratory of Zoonosis Research, Ministry of Education, College of Veterinary Medicine, Jilin University, Changchun, 130062, China.
Tianqi WangCollege of Clinical Medicine, Jilin University, Changchun, 130021, China.
Wenyu HanKey Laboratory of Zoonosis Research, Ministry of Education, College of Veterinary Medicine, Jilin University, Changchun, 130062, China.
Nannan WuShanghai Institute of Phage, Shanghai Public Health Clinical Center, Fudan University, Shanghai, 201508, China. wunannan@shphc.org.cn.
Tongyu ZhuShanghai Institute of Phage, Shanghai Public Health Clinical Center, Fudan University, Shanghai, 201508, China. tyzhu@shphc.org.cn.
Jingmin GuShanghai Institute of Phage, Shanghai Public Health Clinical Center, Fudan University, Shanghai, 201508, China. jingmin0629@163.com.ORCID http://orcid.org/0000-0002-3522-195X

Funding

Jilin Province Science Foundation for Youths 20190103106JHNational Natural Science Foundation of China 31572553National Natural Science Foundation of China 31872505
6 · The paper itself

Abstract

Acinetobacter pittii is an important pathogen causing nosocomial infection worldwide. In this study, a multidrug-resistant A. pittii ABC38 was used as host bacterium to isolate the lytic phage vB_ApiP_XC38. The biological characteristics of vB_ApiP_XC38 were studied and the genome was sequenced and analyzed. vB_ApiP_XC38 belonged to Podoviridae family. The phage had double-stranded genome, which comprised 79,328 bp with 39.58% G+C content displaying very low similarity (< 1% identity) with published genomes of other phages and bacteria. A total of 97 open reading frames (ORFs) were predicted and contained nucleotide metabolism and replication module, structural components module, and lysis module. The ANI, AAI, and phylogenetic analysis indicated that all phages were found distant from vB_ApiP_XC38. Altogether, morphological, genomics, and phylogenetic analysis suggest that vB_ApiP_XC38 is more likely a novel phage of A. pittii.

Indexed as

AcinetobacterBacteriophagesBase CompositionDNA, ViralGenome, ViralGenomicsOpen Reading FramesPhylogenyPodoviridaeDNA, ViralAcinetobacter pittiiGenome analysisOpportunistic pathogenPhage

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.