Evidence map›Paper›PMID 32449105›Full record

Observational studyAging clinical and experimental research2020

Emergency laparotomy in the older patient: factors predictive of 12-month mortality-Salford-POPS-GS. An observational study.

Arturo Vilches-Moraga, Mollie Rowley, Jenny Fox, Haroon Khan, Areej Paracha, Angeline Price, Lyndsay Pearce

Registry-linked trialOpen access · hybridAbstract readObservational Study
In one paragraph

Observational study in Aging clinical and experimental research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06038045 (PROSPER- Electronic Patient Reported OutcomeS to Empower Patients rEcoveR), which is not on this map. Cited by 17 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 6 pooled it
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06038045 completednot on this mapstarted 2023, after this paper: background citation

PROSPER- Electronic Patient Reported OutcomeS to Empower Patients rEcoveR

TypeobservationalSponsorQueen Mary University of LondonRan2023 to 2025Enrolled314ConditionsSurgery, Critical Illness, Trauma
3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 6 syntheses or guidelines pooled it, 35 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Association between mortality and frailty in emergency general surgery: a systematic review and meta-analysis.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2022
    Pooled it
  6. Pooled it
  7. Article
  8. Article
  9. Review
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  11. Impact of preoperative frailty on outcomes in patients subjected to emergency laparotomy: a prospective study.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2025
    Article
  12. Review
  13. Article
  14. Outcomes of emergency laparoscopy in the elderly.Annals of the Royal College of Surgeons of England · 2022
    Observational
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  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Arturo Vilches-MoragaAgeing and Complex Medicine Department, Salford Royal NHS Foundation Trust, Stott Lane, Salford, Manchester, M6HD8, UK. arturo.vilches-moraga@srft.nhs.uk.ORCID http://orcid.org/0000-0001-6221-2066
Mollie RowleyAgeing and Complex Medicine Department, Salford Royal NHS Foundation Trust, Stott Lane, Salford, Manchester, M6HD8, UK.
Jenny FoxAgeing and Complex Medicine Department, Salford Royal NHS Foundation Trust, Stott Lane, Salford, Manchester, M6HD8, UK.
Haroon KhanGeneral Surgery Department, Salford Royal NHS Foundation Trust, Stott Lane, Salford, Manchester, M6HD8, UK.
Areej ParachaGeneral Surgery Department, Salford Royal NHS Foundation Trust, Stott Lane, Salford, Manchester, M6HD8, UK.
Angeline PriceAgeing and Complex Medicine Department, Salford Royal NHS Foundation Trust, Stott Lane, Salford, Manchester, M6HD8, UK.
Lyndsay PearceGeneral Surgery Department, Salford Royal NHS Foundation Trust, Stott Lane, Salford, Manchester, M6HD8, UK.
Salford Royal NHS Foundation Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAlthough high rates of in-hospital mortality have been described in older patients undergoing emergency laparotomy (EL), less is known about longer-term outcomes in this population. We describe factors present at the time of hospital admission that influence 12-month survival in older patients.

methodsObservational study of patients aged 75 years and over, who underwent EL at our hospital between 8th September 2014 and 30th March 2017.

results113 patients were included. Average age was 81.9 ± 4.7 years, female predominance (60/113), 3 (2.6%) lived in a care home, 103 (91.2%) and 79 (69.1%) were independent of personal and instrumental activities of daily living (ADLs) and 8 (7.1%) had cognitive impairment. Median length of stay was 16 days ± 29.9 (0-269); in-hospital mortality 22.1% (25/113), post-operative 30-day, 90-day and 12-month mortality rates 19.5% (22), 24.8% (28) and 38.9% (44). 30-day and 12-month readmission rates 5.7% (5/88) and 40.9% (36). 12-month readmission was higher in frail patients, using the Clinical Frailty Scale (CFS) score (64% 5-8 vs 31.7% 1-4, p = 0.006). Dependency for personal ADLs (6/10 (60%) dependent vs. 38/103 (36.8%) independent, p = 0.119) and cognitive impairment (5/8 (62.5%) impaired vs. 39/105 (37.1%) no impairment, p = 0.116) showed a trend towards higher 12-month mortality. On multivariate analysis, 12-month mortality was strongly associated with CFS 5-9 (HR 5.0403 (95% CI 1.719-16.982) and ASA classes III-V (HR 2.704 95% CI 1.032-7.081).

conclusionFrailty and high ASA class predict increased mortality at 12 months after emergency laparotomy. We advocate early engagement of multi-professional teams experienced in perioperative care of older patients.

Indexed as

Activities of Daily LivingFrailtyAgedAged, 80 and overFemaleFrail ElderlyGeriatric AssessmentHumansLaparotomyLength of StayComprehensive geriatric assessmentEmergency laparotomyFrailtyMortalittyOlder peopleSurgery

Identifiers

PMID32449105
PMCPMC7591437
OpenAlexW3027192823

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.