Evidence map›Paper›PMID 32449069›Full record

ReviewMolecular biology reports2020

Dependence between estrogen sulfotransferase (SULT1E1) and nuclear transcription factor Nrf-2 regulations via oxidative stress in breast cancer.

Aarifa Nazmeen, Guangping Chen, Smarajit Maiti

Open access · greenAbstract readReview
In one paragraph

Review in Molecular biology reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Contribution of n-3 Long-Chain Polyunsaturated Fatty Acids to the Prevention of Breast Cancer Risk Factors.International journal of environmental research and public health · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Aarifa NazmeenDepartment of Biochemistry, Cell & Molecular Therapeutics Lab, Oriental Institute of Science & Technology, Midnapore, 721101, India.
Guangping ChenOklahoma Technology & Research Park, Venture I OSU Laboratory, 1110 S. Innovation Way, Stillwater, OK, 74074, USA.
Smarajit MaitiDepartment of Biochemistry, Cell & Molecular Therapeutics Lab, Oriental Institute of Science & Technology, Midnapore, 721101, India. maitism@rediffmail.com.ORCID http://orcid.org/0000-0002-1354-1303
Czech Academy of Sciences, Oriental Institute · CZ

Funding

Mechanisms and Functions of Human SulfotransferasesR01GM078606 · NIGMS · OKLAHOMA STATE UNIVERSITY STILLWATER · PI CHEN, GUANGPING · 2006 to 2009
$1.1M
ACTIVE SITE STUDIES OF HUMAN SULFOTRANSFERASESR01GM059873 · NIGMS · UNIVERSITY OF ARKANSAS MED SCIS LTL ROCK · PI CHEN, GUANGPING · 2000 to 2003
$759k
NIGMS NIH HHS R01 GM059873NIGMS NIH HHS R01 GM078606
6 · The paper itself

Abstract

Human estrogen sulfotransferase (SULT1E1) and nuclear factor erythroid 2-related factor 2 (Nrf-2) expression influences each other in advanced human breast carcinogenesis. The difference in the metabolism of estradiol (E2) in pre- and post-menopausal women remains to be connected with post-menopausal breast cancer. A synergism between ROS production and E2 generation has been demonstrated. No definite mechanism for simultaneous functions of Nrf2, oxidative stress E2 regulating enzymes (SULT1E1) has been yet clarified. Our present review demonstrates that ROS dependent regulation of Nrf-2 is one of the most important determinants of E2 regulation by altering SULT1E1 expression. This study also focuses the idea that estrogen receptor cased subtypes of cancer may have different molecular environments which has an impact on the therapeutic efficacy.

Indexed as

Breast NeoplasmsCell Line, TumorEstradiolEstrogensFemaleHumansNF-E2-Related Factor 2Oxidative StressSulfotransferasesTranscription FactorsEstradiolEstrogensestrone sulfotransferaseNFE2L2 protein, humanNF-E2-Related Factor 2SulfotransferasesTranscription FactorsBreast cancerEstrogen regulationsNrf-2 and SULT1E1 expressionsOxidative stress

Identifiers

PMID32449069
PMCPMC9248037
OpenAlexW3028327302

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.