Evidence map›Paper›PMID 32449054›Full record

ArticleMycopathologia2020

Trichophyton indotineae sp. nov.: A New Highly Terbinafine-Resistant Anthropophilic Dermatophyte Species.

Rui Kano, Utako Kimura, Maki Kakurai, Junichiro Hiruma, Hiroshi Kamata, Yasushi Suga, Kazutoshi Harada

Abstract read
PubMed Publisher
In one paragraph

Article in Mycopathologia, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 126 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
126citing papers in PubMed, 3 pooled it
17.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

126 citing papers in PubMed, 3 syntheses or guidelines pooled it, 244 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. [Multiple itchy, erythrosquamous skin lesions].Dermatologie (Heidelberg, Germany) · 2026
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  7. Deciphering the genomic landscape ofMicrobial genomics · 2026
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  9. Dermatophytosis: An Update on Global Epidemiology.Journal of fungi (Basel, Switzerland) · 2026
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  10. Review
  11. Article
  12. The emergence of superficial dermatophytosis due toJournal of clinical microbiology · 2026
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  14. The entireAntimicrobial agents and chemotherapy · 2026
    Article
  15. Article
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  17. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2026
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  20. Two cases of sexually transmittedCMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2026
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66 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Rui KanoDepartment of Veterinary Dermatology, Nihon University College of Bioresource Sciences, 1866 Kameino, Fujisawa, Kanagawa, 252-0880, Japan. kanou.rui@nihon-u.ac.jp.
Utako KimuraDepartment of Dermatology, Juntendo University Urayasu Hospital, 2-1-1 Tomioka, Urayasu, Chiba, 279-0021, Japan.
Maki KakuraiKakurai Dermatology Clinic, 905-1, Ojima, Shimotsuma, Ibaraki, 304-0051, Japan.
Junichiro HirumaDepartment of Dermatology, Tokyo Medical University, 6-1-1 Nishishinjuku, Shinjuku-ku, Tokyo, 160-0023, Japan.
Hiroshi KamataDepartment of Veterinary Dermatology, Nihon University College of Bioresource Sciences, 1866 Kameino, Fujisawa, Kanagawa, 252-0880, Japan.
Yasushi SugaDepartment of Dermatology, Juntendo University Urayasu Hospital, 2-1-1 Tomioka, Urayasu, Chiba, 279-0021, Japan.
Kazutoshi HaradaDepartment of Dermatology, Tokyo Medical University, 6-1-1 Nishishinjuku, Shinjuku-ku, Tokyo, 160-0023, Japan.
Juntendo University Urayasu Hospital · JPNihon University · JPTokyo Medical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this report, we describe the first isolation of two highly terbinafine (TRF)-resistant Trichophyton interdigitale-like strains from a Nepali patient and an Indian patient with tinea corporis in Japan. These strains (designated NUBS19006 and NUBS19007) exhibited a TRF minimal inhibitory concentration (MIC) of > 32 mg/L and contained a missense mutation (Phe397Leu) in squalene epoxidase (SQLE) gene. The internal transcribed spacer (ITS) region sequences amplified from the isolates (NUBS19006 and NUBS19007) were 99.5% identical to Japanese isolates of T. interdigitale and T. interdigitale strain CBS 428.63. The homology of region sequences were also 97.6% identical to T. mentagrophytes strain CBS 318.56. Moreover, the ITS sequences amplified from the isolates were 100% identical to highly TRF-resistant strains of T. interdigitale, which were isolated in Delhi, India, and harbored mutations in SQLE. The urease test on Christensen's urease agar was positive for T. mentagrophytes and T. interdigitale after 7 days of incubation. On the other hand, the type strain of T. rubrum CBS 100081

Indexed as

ArthrodermataceaeAntifungal AgentsGenes, FungalHumansIndiaJapanMutation, MissenseNepalSqualene MonooxygenaseTerbinafineTineaAntifungal AgentsSqualene MonooxygenaseTerbinafineDermatophytosisTerbinafine resistanceTinea corporisTrichophyton indotineae

Identifiers

PMID32449054
OpenAlexW3028392977

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.