ArticleSocial psychiatry and psychiatric epidemiology2021
Age-varying associations between lifestyle risk factors and major depressive disorder: a nationally representative cross-sectional study of adolescents.
Article in Social psychiatry and psychiatric epidemiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Interpersonal needs in relation to depression and suicidal ideation in early adolescents: the moderating roles of ADHD and sex.Journal of affective disorders · 2026Article
- The Potential Relationship Between Low Back Pain and Depression: A Comprehensive Review.Brain and behavior · 2025Review
- Associations between wearables vital parameters and self-perceived mood-an ecological momentary assessment study among healthy adolescents.Frontiers in psychology · 2025Article
- The association between dietary quality, sleep duration, and depression symptoms in the general population: findings from cross-sectional NHANES study.BMC public health · 2024Article
- Examining temporal trends in psychological distress and the co-occurrence of common substance use in a population-based sample of grade 7-12 students from 2013 to 2019.Social psychiatry and psychiatric epidemiology · 2024Article
- Longitudinal relationships between lifestyle risk factors and neurodevelopment in early adolescence.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2023Article
- Sedentary Behavior and Physical Activity Associated with Psychosocial Outcomes in Adolescents with Type 1 Diabetes.Pediatric diabetes · 2023Article
- The Effectiveness of the Super Skills for Life (SSL) Programme in Promoting Mental Wellbeing among Institutionalised Adolescents in Malaysia: An Interventional Study.International journal of environmental research and public health · 2022Article
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Authors and funding
12 authors.
Funding
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Abstract
purposeLifestyle risk factors, such as alcohol use, smoking, high body mass index, poor sleep, and sedentary behavior, represent major public health issues for adolescents. These factors have been associated with increased rates of major depressive disorder (MDD). The purpose of this paper is to investigate critical peaks in the prevalence of MDD at certain ages and to examine how these peaks might be amplified or attenuated by the presence of lifestyle risk factors.
methodsA nationally representative sample of adolescents aged 11-17 years old (n = 2967) and time-varying effect models were used to investigate the associations between lifestyle risk factors and the prevalence of MDD by sex.
resultsThe estimated prevalence of MDD significantly increased among adolescents from 4% (95% CI 3-6%) at 13 years of age to 19% (95% CI 15-24%) at 16 years of age. From the age of 13, males were significantly less likely to have a diagnosis of MDD than females with the maximum sex difference occurring at the age of 15 (OR 0.24, 95% CI 0.13-0.47). All lifestyle risk factors were at some point significantly associated with MDD, but these associations did not differ by sex, except for body mass index. DISCUSSION: These findings suggest that interventions designed to prevent the development of depression should be implemented in early adolescence, ideally before or at the age of 13 and particularly among young females given that the prevalence of MDD begins to rise and diverge from young males. Interventions should also simultaneously address lifestyle risk factors and symptoms of major depression.
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