ArticleThe Journal of veterinary medical science2020
Long-term outcome and progression of osteoarthritis in uncomplicated cases of cranial cruciate ligament rupture treated by tibial plateau leveling osteotomy in dogs.
Article in The Journal of veterinary medical science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Surgical treatment of cranial cruciate ligament disease in dogs using Tibial Plateau Leveling Osteotomy or Tibial Tuberosity Advancement-A systematic review with a meta-analytic approach.Frontiers in veterinary science · 2022Pooled it
- Modified Tibial Plateau Levelling Osteotomy in a Cat With a Cranial Cruciate Ligament Rupture and a Concurrent Medial Patellar Luxation.Veterinary medicine and science · 2026Article
- Intra-articular injection of allogeneic canine adipose-derived stem cell enriched secretome in dogs undergoing tibial plateau leveling osteotomy: a prospective double-blind and randomized pilot trial.Veterinary research communications · 2026Article
- Combined tibial plateau leveling osteotomy and autologous conditioned serum for functional recovery and delayed osteoarthritis progression in dogs with cranial cruciate ligament rupture.Frontiers in veterinary science · 2026Article
- Three-dimensional analysis of femoral tunnel placement in canine cranial cruciate ligament reconstruction.BMC veterinary research · 2025Article
- Efficacy of a joint supplement containing eggshell membrane among other ingredients to improve the mobility of dogs with osteoarthritis: a multicenter double-blind randomized placebo-controlled study.Frontiers in veterinary science · 2025Article
- Effect of ELHLD peptide for stifle function recovery after tibial plateau leveling osteotomy in dogs.Journal of veterinary science · 2025Article
- Biomechanical effects of cranial closing wedge osteotomy on joint stability in normal canine stifles: an ex vivo study.BMC veterinary research · 2024Article
- Economic Considerations on Costs and Pricing of Two Surgical Techniques for Treating Cranial Cruciate Disease in Dogs.Animals : an open access journal from MDPI · 2023Article
- Associations between meniscal tears and various degrees of osteoarthritis among dogs undergoing TPLO for cranial cruciate ligament rupture.BMC research notes · 2023Article
- Etiopathogenesis of Canine Cruciate Ligament Disease: A Scoping Review.Animals : an open access journal from MDPI · 2023Article
- The effect of joint orientation on passive movement of the dog's stifle.Frontiers in veterinary science · 2023Article
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- Comparison of grapiprant and meloxicam for management of postoperative joint pain in dogs: A randomized, double-blinded, prospective clinical trial.Journal of veterinary internal medicineArticle
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The object of this study is to evaluate the long-term outcome of hind limb weight-bearing function and progression of stifle osteoarthritis (OA) after tibial plateau leveling osteotomy (TPLO). Groups were classified by the degree of cranial cruciate ligament (CrCL) damage and presence or absence of medial meniscus damage as macroscopically evaluated during surgery. Weight-bearing function was assessed via the peak vertical force (PVF), and OA progression was assessed via the radiographic OA score (OAS) preoperatively and 1, 3, 6, 12, 18, 24, and 36 months postoperatively. In all stifles, PVF was significantly higher within 6 months postoperatively than preoperatively, and this high ratio was maintained for 36 months. The OAS was significantly higher 24 months postoperatively than preoperatively in stifles with a partial CrCL tear, and significantly increased at each timepoint after 3 months postoperatively in stifles with complete CrCL rupture. The OAS remained consistently lower in stifles with a partial CrCL tear and no treatment of the medial meniscus than in stifles with complete rupture. Thus, after TPLO, the weight-bearing function improved in the early postoperative period and was maintained for as long as 36 months. Although OA progressed over time after TPLO, the progression was more gradual in stifles with partial tears than in those with complete rupture. Canine patients would benefit from earlier surgical intervention through development of technology that enables early detection of ligament degeneration.
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