Evidence map›Paper›PMID 32448358›Full record

Trial reportItalian journal of pediatrics2020

A randomized controlled study of immediate versus delayed umbilical cord clamping in infants born by elective caesarean section.

Giuseppe De Bernardo, Maurizio Giordano, Rita De Santis, Paola Castelli, Desiree Sordino, Daniele Trevisanuto, Giuseppe Buonocore, Serafina Perrone

Registry-linked trialOpen access · goldAbstract readComparative StudyRandomized Controlled Trial
In one paragraph

Trial report in Italian journal of pediatrics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03878602 (Delayed Umbilical Cord Clamping in Elective Caesarean Section), which is not on this map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
2.0field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03878602 nacompletednot on this map

Delayed Umbilical Cord Clamping in Elective Caesarean Section: What Are the Benefits

TypeinterventionalSponsorFondazione Poliambulanza Istituto OspedalieroRan2018 to 2019Enrolled142ConditionsDelayed Cord ClampingArmsDelayed umbilical cord clamping, Immediate umbilical cord clamping
3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 35 citations in OpenAlex.

  1. Guideline
  2. Pooled it
  3. Trial
  4. Article
  5. Review
  6. Comparing delayed cord clamping and umbilical cord milking during elective cesarean section for the neonatal outcome.European journal of obstetrics & gynecology and reproductive biology: X · 2023
    Article
  7. Article
  8. Article
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 8 institutions in 1 country.

Giuseppe De BernardoDivision of Pediatrics Neonatology and NICU, Ospedale Buon Consiglio Fatebenefratelli, Via Manzoni 220, 80123, Naples, Italy. pinodebtin@gmail.com.ORCID http://orcid.org/0000-0001-5348-6743
Maurizio GiordanoDepartment of Clinical Medicine and Surgery, Federico II University, Naples, Italy.
Rita De SantisSchool of specialization in Pediatrics, Catholic University of the Sacred Heart Faculty of Medicine and Surgery, Rome, Italy.
Paola CastelliSchool of specialization in Pediatrics, University of Pavia Faculty of Medicine and Surgery, Pavia, Italy.
Desiree SordinoDepartment of Emergency-NICU, A.O.R.N. Santobono-Pausilipon, Naples, Italy.
Daniele TrevisanutoDepartment of Woman's and Child's Health, University of Padova, Padova, Italy.
Giuseppe BuonocoreDepartment of Molecular and Developmental Medicine, University of Siena, Siena, Italy.
Serafina PerroneDepartment of Medicine and Surgery, University of Parma, Parma, Italy.
Federico II University Hospital · ITOspedale Buon Consiglio Fatebenefratelli · ITSantobono Children's Hospital · ITUniversità Cattolica del Sacro Cuore · ITUniversity of Padua · ITUniversity of Parma · ITUniversity of Pavia · ITUniversity of Siena · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDelayed umbilical cord clamping is associated with greater haemoglobin concentration and iron storage between 3 and 6 months of life and with less need of blood transfusion and lower incidence of neonatal hypotension compared to early umbilical cord clamping.

methodsThe aim was to test the hypothesis that delayed cord clamping is better than early cord clamping in term infants born by elective caesarean section. Group A was subjected to immediate cord clamping while in the Group B, the umbilical cord was clamped 1 min after birth. Primary aim was revealed the difference in pre-ductal saturation between two groups while secondary aim was investigating the difference in HR, Ht, bilirubin and glycaemia. Pre-ductal SpO

results132 newborns were enrolled in the study and allocated in ratio 1:1 to group A or B. Delayed cord clamping did not improve SpO

conclusionsGroup B did not reveal any differences in SpO

trial registrationUmbilical Cord Clamping: What Are the Benefits; NCT03878602. Registered 18 March 2019 retrospectively registered.

Indexed as

Cesarean SectionAdultBilirubinBlood Gas AnalysisBlood GlucoseBody TemperatureConstrictionFemaleHeart RateHematocritHumansInfant, NewbornMalePregnancyTime FactorsUmbilical CordBilirubinBlood GlucoseDelayed cord clampingElective caesarean sectionNewborns

Identifiers

PMID32448358
PMCPMC7247269
OpenAlexW3028495243

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.