Evidence map›Paper›PMID 32448270›Full record

ArticleBMC surgery2020

The effect of laparoscopy on mast cell degranulation and mesothelium thickness in rats.

Hery Poerwosusanta, Gunadi, Zairin Noor, Ika Kustiyah Oktaviyanti, Karyono Mintaroem, Bambang Pardjianto, Moch Aris Widodo, Edi Widjajanto

Open access · goldAbstract read
In one paragraph

Article in BMC surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Hery PoerwosusantaDoctoral Study Program, Faculty of Medicine, Universitas Brawijaya, Malang, Indonesia. herpoerwo@ulm.ac.id.ORCID http://orcid.org/0000-0003-2786-598X
GunadiPediatric Surgery Division, Department of Surgery, Faculty of Medicine, Public Health and Nursing, Universitas Gajah Mada /Dr. Sardjito Hospital, Yogyakarta, Indonesia.ORCID http://orcid.org/0000-0002-4707-6526
Zairin NoorDepartment of Surgery, Ulin General Hospital, Faculty of Medicine, Universitas Lambung Mangkurat, Banjarmasin, Indonesia.ORCID http://orcid.org/0000-0001-6273-1739
Ika Kustiyah OktaviyantiDepartment of Anatomical Pathology, Faculty of Medicine, Universitas Lambung Mangkurat, Banjarmasin, Indonesia.ORCID http://orcid.org/0000-0002-8487-6792
Karyono MintaroemDepartment of Biomedical Science, Faculty of Medicine, Universitas Brawijaya, Malang, Indonesia.ORCID http://orcid.org/0000-0002-7442-1401
Bambang PardjiantoDepartment of Biomedical Science, Faculty of Medicine, Universitas Brawijaya, Malang, Indonesia.ORCID http://orcid.org/0000-0001-7310-1898
Moch Aris WidodoDepartment of Biomedical Science, Faculty of Medicine, Universitas Brawijaya, Malang, Indonesia.ORCID http://orcid.org/0000-0002-5444-7989
Edi WidjajantoDepartment of Biomedical Science, Faculty of Medicine, Universitas Brawijaya, Malang, Indonesia.ORCID http://orcid.org/0000-0001-5394-7634
University of Brawijaya · IDLambung Mangkurat University · ID

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLaparoscopy induces adhesion due to ischemia-reperfusion injury. However, the detail pathomechanism is poorly understood. This study aimed to investigate the impact of laparoscopy on mast cell and mesothelium morphological changes in the rat.

methodsForty-nine males of Sprague-Dawley Rattus norvegicus were divided into four groups: a) control and b) intervention groups P1, P2, and P3 that underwent 60 min laparoscopic using carbon dioxide (CO

resultsH

conclusionsOur study shows that laparoscopy in rats increases mast cell infiltration and degranulation, which also results in and correlates with a decrease in mesothelial thickness.

Indexed as

AnimalsCell DegranulationEpitheliumHydrogen PeroxideIntestine, SmallLaparoscopyLiverMaleMalondialdehydeMast CellsOxidative StressRatsRats, Sprague-DawleyReperfusion InjuryHydrogen PeroxideMalondialdehydeLaparoscopic proceduremast cell infiltration and degranulationmesothelium thicknessoxidative stressRattus norvegicus

Identifiers

PMID32448270
PMCPMC7247274
OpenAlexW3026095863

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.