ArticleItalian journal of pediatrics2020
Association between maternal HIV infection and birthweight in a tertiary hospital in southern Ethiopia: retrospective cohort study.
Article in Italian journal of pediatrics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 4 of them syntheses that pooled it.
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Who cites it
12 citing papers in PubMed, 4 syntheses or guidelines pooled it, 23 citations in OpenAlex.
- The effect of maternal anemia during pregnancy on low birth weight in Ethiopia; a systematic review and meta-analysis.BMC pregnancy and childbirth · 2025Pooled it
- Effect of maternal HIV infection on birth outcomes among HIV positive women in Sub Saharan Africa: a systematic review and meta-analysis.BMC public health · 2025Pooled it
- Association between anemia in pregnancy with low birth weight and preterm birth in Ethiopia: A systematic review and meta-analysis.PloS one · 2024Pooled it
- Maternal low and high hemoglobin concentrations and associations with adverse maternal and infant health outcomes: an updated global systematic review and meta-analysis.BMC pregnancy and childbirth · 2023Pooled it
- Anti-hypertensive use for non-severe gestational hypertension in Botswana: A case-control study.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2022Trial
- Combined effects of bacterial vaginal colonization and HIV on pregnancy outcomes: A Systematic Review and Meta-analysis.Research square · 2026Article
- Prevalence and associated factors with low birth weight among human immunodeficiency virus exposed infants between 2004 and 2021 in Hubei, China: a retrospective cohort study.BMC public health · 2025Article
- Article
- Fetal Growth Restriction and Clinical Parameters of Newborns from HIV-Infected Romanian Women.Medicina (Kaunas, Lithuania) · 2023Article
- Perinatal Exposure to HIV Infection: The Experience of Craiova Regional Centre, Romania.Healthcare (Basel, Switzerland) · 2022Article
- Effects of HIV Infection on Pregnancy Outcomes Among Women Attending Antenatal Care in Referral Hospitals of the Amhara Regional State, Ethiopia: A Prospective Cohort Study.International journal of women's health · 2022Article
- Determinants and outcomes of low birth weight among newborns at a tertiary hospital in Zambia: A retrospective cohort study.Annals of African medicineArticle
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHuman Immunodeficiency Virus (HIV) infection and low birth weight (LBW) continue to be significant public health concerns in many low-income countries including Ethiopia. Yet the effect of maternal HIV infection on birth weight has not been thoroughly explored and the existing studies reported opposing findings. We examined the association between maternal HIV infection and LBW in a tertiary hospital in Southern Ethiopia.
methodsA retrospective cohort study was conducted based on the medical records of 277 HIV-negative and 252 HIV-positive mothers who gave singleton live birth between September 2014 to August 2017 in Hawassa University Comprehensive Specialized Hospital, Southern Ethiopia. The recodes were identified using systematic sampling approach and relevant information were extracted by using pretested extraction form. Multivariable binary logit model was fitted to examine the relationship between the exposure and outcome while adjusting for potential confounders. Adjusted odds ratio (AOR) and 95% confidence intervals (CI) is used for summarizing the findings of the analysis.
resultsThe mean (± standard deviation) birth weight of infants born to HIV-negative women (3.1 ± 0.7 kg) was significantly higher than those born to HIV-positive counterparts (3.0 ± 0.6 kg) (p = 0.020). The prevalence of LBW was also significantly higher in the HIV-exposed group (22.2%) than the non-exposed group (13.7%) (p = 0.011). In the logit model adjusted for multiple covariates, HIV-positive women had four times increased odds than HIV-negative women to give birth to LBW infant(AOR = 4.03, 95% CI: 2.01-8.06). Other significant predictors of LBW were rural place of residence (AOR = 2.04, 95% CI: 1.16-3.60), prenatal anemia (AOR = 3.17, 95% CI: 1.71-5.90), chronic hypertension (AOR = 3.68, 95% CI: 1.10-12.46) and preeclampsia (AOR = 6.80, 95% CI: 3.00-15.38).
conclusionMaternal HIV infection is associated with increased odds of LBW. HIV prevention activities are also likely to contribute for the reduction of LBW.
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