Trial reportBMC medical imaging2020
Application of CareDose 4D combined with Karl 3D technology in the low dose computed tomography for the follow-up of COVID-19.
Trial report in BMC medical imaging, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Reporting and design of randomized controlled trials for COVID-19: A systematic review.Contemporary clinical trials · 2021Pooled it
- Achieving low radiation dose and contrast agents dose in coronary CT angiography at 60-kVp ultra-low tube voltage.BMC medical imaging · 2025Article
- Reduced-dose deep learning iterative reconstruction for abdominal computed tomography with low tube voltage and tube current.BMC medical informatics and decision making · 2024Article
- Standardization of a CT Protocol for Imaging Patients with Suspected COVID-19-A RACOON Project.Bioengineering (Basel, Switzerland) · 2024Article
- Low-Dose Chest CT Protocols for Imaging COVID-19 Pneumonia: Technique Parameters and Radiation Dose.Life (Basel, Switzerland) · 2023Review
- Joint application of hybrid iterative reconstruction and adaptive filters on neck-and-shoulder CT imaging: A clinical evaluation.Journal of applied clinical medical physics · 2022Article
- Applying a CT texture analysis model trained with deep-learning reconstruction images to iterative reconstruction images in pulmonary nodule diagnosis.Journal of applied clinical medical physics · 2022Article
- CHEST CT USAGE IN COVID-19 PNEUMONIA: MULTICENTER STUDY ON RADIATION DOSES AND DIAGNOSTIC QUALITY IN BRAZIL.Radiation protection dosimetry · 2021Article
- Overview of Technologies Implemented During the First Wave of the COVID-19 Pandemic: Scoping Review.Journal of medical Internet research · 2021Article
- The reliability of low-dose chest CT for the initial imaging of COVID-19: comparison of structured findings, categorical diagnoses and dose levels.Diagnostic and interventional radiology (Ankara, Turkey) · 2021Article
- CT-based radiomics for predicting the rapid progression of coronavirus disease 2019 (COVID-19) pneumonia lesions.The British journal of radiology · 2021Article
- Variations in CT Utilization, Protocols, and Radiation Doses in COVID-19 Pneumonia: Results from 28 Countries in the IAEA Study.Radiology · 2021Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCoronavirus disease 2019 (COVID-19) is a highly infectious disease caused by the new coronavirus. Previous studies have shown that the chest CT examination plays an important role in the diagnosis and monitoring of COVID-19. However, some patients with COVID-19 had low white blood cell counts and reduced lymphocyte ratios. Multiple CT examinations may cause radiation damages as well as increase the apoptosis of peripheral blood lymphocytes. A new low-dose CT method should be developed because the regular CT may aggravate the disease.
methodSixty cases were randomly divided into the study group (n = 30) and control group (n = 30). The lung window was reconstructed by Karl 3D iterative technique in the study group. The image quality was subjectively evaluated by two senior chest group diagnostic physicians using a 5-point double-blind method. The value of CT measurement and its standard deviation (SD) was used as an objective evaluation criteria. The volume of CT dose index (CTDI
resultThere was no significant difference in the occurrence rates of ground glass opacities, consolidation, crazy-paving pattern, fiber cable shadow and axial interstitial thickening between the study group and control group (p > 0.05). In addition, no significant difference was found for the subjective score of overall image quality and image noise level (SD) between the two groups (p > 0.05). However, significant differences was found in CTDI
conclusionCareDose 4D low-dose scanning combined with Karl 3D iterative reconstruction technology can not only greatly reduce the radiation dose, but also provide images that meet the diagnostic criteria of COVID-19, which can be used as a routine method for the follow-up of COVID-19 patients.
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