Evidence map›Paper›PMID 32447878›Full record

ArticleClinical and molecular hepatology2020

Clinical application of ultrasonography-guided percutaneous liver biopsy and its safety over 18 years.

Young Chang, Jun Il Kim, Bora Lee, Sang Gyune Kim, Min Jung Jung, Young Seok Kim, Soung Won Jeong, Jae Young Jang, Jeong-Ju Yoo

Open access · goldAbstract read
In one paragraph

Article in Clinical and molecular hepatology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 29 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Young ChangDepartment of Internal Medicine, Soonchunhyang University College of Medicine, Seoul, Korea.
Jun Il KimDepartment of Internal Medicine, Soonchunhyang University College of Medicine, Bucheon, Korea.
Bora LeeDepartment of Biostatistics, Chung-Ang University Graduate School, Seoul, Korea.
Sang Gyune KimDepartment of Internal Medicine, Soonchunhyang University College of Medicine, Bucheon, Korea.
Min Jung JungDepartment of Pathology, Soonchunhyang University College of Medicine, Bucheon, Korea.
Young Seok KimDepartment of Internal Medicine, Soonchunhyang University College of Medicine, Bucheon, Korea.
Soung Won JeongDepartment of Internal Medicine, Soonchunhyang University College of Medicine, Seoul, Korea.
Jae Young JangDepartment of Internal Medicine, Soonchunhyang University College of Medicine, Seoul, Korea.
Jeong-Ju YooDepartment of Internal Medicine, Soonchunhyang University College of Medicine, Bucheon, Korea.
Soonchunhyang University · KRChung-Ang University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimsLiver biopsy (LB) remains the gold standard for the evaluation of liver disease. However, over the past two decades, many noninvasive tests have been developed and utilized in clinical practice as alternatives to LB. The aim of this study was to evaluate the clinical use and safety of LB in the era of noninvasive assessment of liver fibrosis.

methodsThis retrospective study included 1,944 consecutive cases of LB performed between 2001 and 2018 in a tertiary hospital. All of the LBs were conducted under ultrasonography guidance with 18-gauge cutting needles.

resultsLBs were performed an average of approximately 108 times per year during the study period. Chronic hepatitis B (25.3%) and suspected malignancy (20.5%) were the two most common indications for LB. The use of LB for nonalcoholic fatty liver disease increased from 8.1% to 17.2% in the past 5 years compared to the last 10 years, while that for viral hepatitis decreased from 40.3% to 18.9%. Discordance rate between the suspected diagnosis and the final diagnosis was 2.6% (51 cases). The overall rate of major adverse events was 0.05% (one case), which involved delayed bleeding at the biopsy site. Liver cirrhosis was observed in 563 cases (28.9%), and the presence of cirrhosis did not affect the frequency of complications (P=0.289).

conclusionLB is widely used in clinical practice as an irreplaceable diagnostic tool, even in the era of noninvasiveness. Ultrasonography-guided LB can be performed safely in patients with liver cirrhosis.

Indexed as

Endoscopic Ultrasound-Guided Fine Needle AspirationAdultFemaleHemorrhageHepatitis, Viral, HumanHumansLiverLiver CirrhosisLiver DiseasesMaleMiddle AgedNon-alcoholic Fatty Liver DiseaseRetrospective StudiesComplicationIndicationLiver biopsy

Identifiers

PMID32447878
PMCPMC7364354
OpenAlexW3027444221

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.