Evidence map›Paper›PMID 32447753›Full record

ArticleEuropean journal of dentistry2020

The Macrophage Responses during Diabetic Oral Ulcer Healing by Liquid Coconut Shell Smoke: An Immunohistochemical Analysis.

Meircurius Dwi Condro Surboyo, Fatma Yasmin Mahdani, Diah Savitri Ernawati, Andari Sarasati, Fianza Rezkita

Open access · hybridAbstract read
In one paragraph

Article in European journal of dentistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Phytochemical Profiling and Wound Healing Activity ofJournal of experimental pharmacology · 2024
    Article
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  15. CaCOJournal of oral biology and craniofacial research
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Meircurius Dwi Condro SurboyoDepartment of Oral Medicine, Faculty of Dental Medicine, Universitas Airlangga, Surabaya, Indonesia.ORCID 0000-0002-6052-2287
Fatma Yasmin MahdaniDepartment of Oral Medicine, Faculty of Dental Medicine, Universitas Airlangga, Surabaya, Indonesia.
Diah Savitri ErnawatiDepartment of Oral Medicine, Faculty of Dental Medicine, Universitas Airlangga, Surabaya, Indonesia.
Andari SarasatiDepartment of Dental Science, Faculty of Dental Medicine, Universitas Airlangga, Surabaya, Indonesia.
Fianza RezkitaDepartment of Dental Science, Faculty of Dental Medicine, Universitas Airlangga, Surabaya, Indonesia.
Airlangga University · ID

Funding

1408/UN3/2019 the Faculty of Dental Medicine - Universitas Airlangga, Surabaya, Indonesia 2019
6 · The paper itself

Abstract

objectivesLiquid coconut shell smoke (LC-SS) is used in natural food preservation for a long history. The purpose of this study was to analyze the role of LC-SS in macrophage responses during diabetic oral ulcer healing as medication. MATERIALS AND

methodsOral ulcers were induced in the labial lower mucosa of the research subjects using a round steel blade following diabetic induction by means of alloxan. Twenty-four diabetic Wistar rats presenting oral ulcers were divided into two groups, a test group, which was given topical treatment of LC-SS and a control group, which was given benzydamine hydrochloride (BHCl). The role of LC-SS in macrophages was assessed by means of immunohistochemistry for nuclear factor kappa B (NF-κB) and tumor necrosis factor-α (TNF-α) expression.

resultLC-SS increased macrophages compared with BHCl (

conclusionLC-SS has a stronger effect compared with BHCl on diabetic oral ulcer healing by increasing macrophage response to produce TNF-α while decreasing NF-κB expression.

Identifiers

PMID32447753
PMCPMC7440958
OpenAlexW3027495505

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.