Evidence map›Paper›PMID 32447741›Full record

ArticleDigestive diseases and sciences2021

Ultrasonographic (US) Two-Dimensional Measurement of Spleen Is Superior to Traditional Length Measurement Alone in Diagnosing Cirrhosis.

Felix H Lui, Patrick Ma, Mohammad Helmy, Ke-Qin Hu

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Digestive diseases and sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 54% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Felix H LuiDepartment of Gastroenterology/Hepatology, School of Medicine, University of California, Irvine, 101 the City Drive, Building 22C, Room 1503, Orange, CA, 92868, USA.
Patrick MaDepartment of Gastroenterology/Hepatology, School of Medicine, University of California, Irvine, 101 the City Drive, Building 22C, Room 1503, Orange, CA, 92868, USA.
Mohammad HelmyDepartment of Radiology, School of Medicine, University of California, Irvine, Orange, CA, USA.
Ke-Qin HuDepartment of Gastroenterology/Hepatology, School of Medicine, University of California, Irvine, 101 the City Drive, Building 22C, Room 1503, Orange, CA, 92868, USA. Kqhu@hs.uci.edu.
University of California, Irvine · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSplenomegaly measured by spleen length has been an imaging evidence for cirrhosis. However, data remains lacking on the value of other US findings for diagnosing cirrhosis. This study evaluated the value of spleen two-dimensional measurements (2D, i.e., length × thickness) in diagnosing cirrhosis by comparing with other US parameters.

methodsA retrospective study on 297 cohort 1 patients with clinical/imaging diagnosis of cirrhosis was conducted. Spleen length and thickness were measured via US imaging and compared with other US parameters using statistical analysis to assess their value in diagnosing cirrhosis. A separate 161 cohort 2 patients with histological fibrosis staging was used to validate the findings from the cohort 1.

resultsUsing 297 cohort 1 patients, US findings of spleen length > 12 cm (50.6% vs. 9.6%, p < 0.001); spleen thickness > 4 cm (78.2% vs. 21%, p < 0.001); and spleen 2D > 46 cm

conclusionUsing both testing and validation cohorts, we demonstrated that spleen 2D > 46 cm

Indexed as

AgedCohort StudiesFemaleHumansLiver CirrhosisMaleMiddle AgedRetrospective StudiesSpleenSplenomegalyUltrasonographyCirrhosisDiagnosisSpleenSplenomegalyUltrasonography

Identifiers

PMID32447741
OpenAlexW3028589595

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.