Evidence map›Paper›PMID 32447642›Full record

ReviewClinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico2020

Potential biomarkers for early detection of pancreatic ductal adenocarcinoma.

D Kriz, D Ansari, R Andersson

Open access · hybridAbstract readReview
In one paragraph

Review in Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 18 citations in OpenAlex.

  1. Overcoming tumour resistance in cancer immunotherapy through predictive and pharmacodynamic biomarkers.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

D KrizDepartment of Surgery, Clinical Sciences Lund, Skåne University Hospital, Lund University, Lund, Sweden.
D AnsariDepartment of Surgery, Clinical Sciences Lund, Skåne University Hospital, Lund University, Lund, Sweden.
R AnderssonDepartment of Surgery, Clinical Sciences Lund, Skåne University Hospital, Lund University, Lund, Sweden. roland.andersson@med.lu.se.ORCID http://orcid.org/0000-0003-0778-8630
Lund University · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pancreatic cancer has the highest mortality amongst all major organ cancers. Early detection is key to reduce deaths related to pancreatic cancer. However, early detection has been challenged by the lack of non-invasive biomarkers with enough sensitivity and specificity to allow for screening. The gold standard is still carbohydrate antigen (CA 19-9), against which all new biomarkers must be evaluated. In this paper, we describe recent progress in the development of new pancreatic cancer biomarkers, focusing on proteins, metabolites, and genetic and epigenetic biomarkers. Although several promising biomarkers have been identified, they are all derived from retrospective studies and additional prospective studies are needed to confirm their clinical validity.

Indexed as

Biomarkers, TumorEarly Detection of CancerAutoantibodiesCA-19-9 AntigenCarcinoma, Pancreatic DuctalEpigenesis, GeneticGenetic MarkersHumansNeoplasm ProteinsPancreatic NeoplasmsSalivaAutoantibodiesBiomarkers, TumorCA-19-9 AntigenGenetic MarkersNeoplasm ProteinsBiomarkersEarly detectionPancreatic cancerSensitivitySpecificity

Identifiers

PMID32447642
PMCPMC7578134
OpenAlexW3027744910

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.