ArticlePlant foods for human nutrition (Dordrecht, Netherlands)2020
St. John's Wort Herbal Teas - Biological Potential and Chemometric Approach to Quality Control.
Article in Plant foods for human nutrition (Dordrecht, Netherlands), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Rare Prenyllipids in Wild St. John's Wort During Three Harvest Seasons.Molecules (Basel, Switzerland) · 2025Article
- Documentary Analysis ofPharmaceuticals (Basel, Switzerland) · 2024Review
- Biological Activity of Genus Hypericum Sect.Molecules (Basel, Switzerland) · 2023Article
- Herbal species authentication by melting fingerprint coupled with high resolution melting analysis (MF-HRM).Molecular biology reports · 2023Article
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Authors and funding
9 authors.
Funding
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Abstract
St. John's wort has been used for centuries in traditional medicine of many cultures, and nowadays it is well-known as a clinically important antidepressant drug. Considering the rising market demand for Hyperici herba, quality control of crude drug is of paramount importance. In this paper we performed HPLC-DAD chemical profiling of St. John's wort tea samples obtained at local markets, pharmacies and health food stores in the Balkan Peninsula countries, Austria and Turkey. Furthermore, water alcoholic extracts of the collected samples were evaluated in terms of their antioxidant potential, as well as the ability to inhibit biologically important enzymes such as acetylcholinesterase, monoamine oxidases A and B (MAO-A and MAO-B), α-amylase and α-glucosidase. Significant variability within the samples in the quantities of hypericin, hyperforin, rutin, quercetin, gallic, chlorogenic, caffeic and p-hydroxybenzoic acid was noticed. Chemotaxonomic modelling enabled the identification of three clusters of samples based on the quantities of rutin, hypericin and hyperforin. Generally, the extracts exhibited a significant potential to inhibit MAO-A (median IC
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Registered trials
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