Evidence map›Paper›PMID 32447579›Full record

ArticleBiological trace element research2021

Age-Related Effects of Orthovanadate Nanoparticles Involve Activation of GSH-Dependent Antioxidant System in Liver Mitochondria.

Yuri V Nikitchenko, Vladimir K Klochkov, Nataliya S Kavok, Nina A Karpenko, Svetlana L Yefimova, Irina V Nikitchenko, Anatoly I Bozhkov

Erratum issuedAbstract read
PubMed Publisher
In one paragraph

Article in Biological trace element research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Yuri V NikitchenkoBiology Research Institute, Karazin Kharkiv National University, pl. Svobody 4, Kharkiv, 61000, Ukraine.
Vladimir K KlochkovInstitute for Scintillation Materials, National Academy of Sciences of Ukraine, 60 Nauky Ave., Kharkiv, 61072, Ukraine.ORCID https://orcid.org/0000-0002-8080-1195
Nataliya S KavokInstitute for Scintillation Materials, National Academy of Sciences of Ukraine, 60 Nauky Ave., Kharkiv, 61072, Ukraine. kavok@isma.kharkov.ua.ORCID https://orcid.org/0000-0002-2429-2832
Nina A KarpenkoInstitute for Scintillation Materials, National Academy of Sciences of Ukraine, 60 Nauky Ave., Kharkiv, 61072, Ukraine.ORCID https://orcid.org/0000-0001-9709-3511
Svetlana L YefimovaInstitute for Scintillation Materials, National Academy of Sciences of Ukraine, 60 Nauky Ave., Kharkiv, 61072, Ukraine.ORCID https://orcid.org/0000-0003-2092-1950
Irina V NikitchenkoBiology Research Institute, Karazin Kharkiv National University, pl. Svobody 4, Kharkiv, 61000, Ukraine.ORCID https://orcid.org/0000-0001-5858-3382
Anatoly I BozhkovBiology Research Institute, Karazin Kharkiv National University, pl. Svobody 4, Kharkiv, 61000, Ukraine.ORCID https://orcid.org/0000-0001-8418-5716
National Academy of Sciences of Ukraine · UAV. N. Karazin Kharkiv National University · UA

Funding

the State Fund For Fundamental Research project № Ф64/29-2016
6 · The paper itself

Abstract

Vanadium is an important ultra-trace element nowadays attracting attention with particular emphasis on medical application. But the therapeutic application of vanadium-based drugs is still questionable and restricted due to some toxic side effects. It was found that unique redox properties of vanadium in nanoform provided antioxidant activity and prevented oxidative disturbance in cells in vitro. Though, on the organism level, ambiguous effects of vanadium-based nanoparticles were observed. In this study, the age-related features of prooxidant/antioxidant balance in blood serum and liver mitochondrial and postmitochondrial fractions of 3 and 18-month-old Wistar male rats treated with orthovanadate nanoparticles (GdVO

Indexed as

AntioxidantsNanoparticlesAnimalsGlutathioneGlutathione PeroxidaseLiverMaleMitochondria, LiverRatsRats, WistarReproducibility of ResultsVanadatesAntioxidantsGlutathioneGlutathione PeroxidaseVanadatesGdVO4/Eu3+ nanoparticlesMale ratsMitochondriaProoxidant/antioxidant balanceVanadium

Identifiers

PMID32447579
OpenAlexW3027362696

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.