Evidence map›Paper›PMID 32447546›Full record

ReviewCell stress & chaperones2020

The renal antioxidative effect of losartan involves heat shock protein 70 in proximal tubule cells.

Patricia G Vallés, Victoria Bocanegra, Valeria V Costantino, Andrea F Gil Lorenzo, María Eugenia Benardon, Valeria Cacciamani

Open access · greenAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Cell stress & chaperones, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. International journal of molecular sciences · 2024
    Article
  2. Cells · 2022
    Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Patricia G VallésÁrea de Fisiopatología, Departamento de Patología, Facultad de Ciencias Médicas, Universidad Nacional de Cuyo, Mendoza, Argentina. pvalles@fcm.uncu.edu.ar.
Victoria BocanegraIMBECU CONICET (National Council of Scientific and Technical Research of Argentina), Mendoza, Argentina.
Valeria V CostantinoIMBECU CONICET (National Council of Scientific and Technical Research of Argentina), Mendoza, Argentina.
Andrea F Gil LorenzoÁrea de Fisiopatología, Departamento de Patología, Facultad de Ciencias Médicas, Universidad Nacional de Cuyo, Mendoza, Argentina.
María Eugenia BenardonÁrea de Fisiopatología, Departamento de Patología, Facultad de Ciencias Médicas, Universidad Nacional de Cuyo, Mendoza, Argentina.
Valeria CacciamaniIMBECU CONICET (National Council of Scientific and Technical Research of Argentina), Mendoza, Argentina.
Universidad Nacional de Cuyo · ARInstituto de Medicina y Biología Experimental de Cuyo · ARConsejo Nacional de Investigaciones Científicas y Técnicas · AR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Angiotensin II exerts a cardinal role in the pathogenesis of hypertension and renal injury via action of angiotensin II type 1 (AT

Indexed as

Acute Kidney InjuryAngiotensin IIAnimalsAntioxidantsHSP70 Heat-Shock ProteinsHypertensionKidney Tubules, ProximalLosartanNADPH Oxidase 4RatsRats, Inbred SHRAngiotensin IIAntioxidantsHSP70 Heat-Shock ProteinsLosartanNADPH Oxidase 4Nox4 protein, ratAngiotensin IIHeat shock proteins 70 (HSP70)LosartanNox4 NADPH oxidaseRenal proximal tubule cells

Identifiers

PMID32447546
PMCPMC7479660
OpenAlexW3026794895

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.