Evidence map›Paper›PMID 32447465›Full record

ArticleNaunyn-Schmiedeberg's archives of pharmacology2020

The involvement of GABAergic system in the antidepressant-like effect of agmatine.

Vivian Binder Neis, Axel Fogaça Rosado, Gislaine Olescowicz, Morgana Moretti, Priscila Batista Rosa, Nicole Platt, Ana Lúcia S Rodrigues

Abstract read
PubMed Publisher
In one paragraph

Article in Naunyn-Schmiedeberg's archives of pharmacology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Vivian Binder NeisDepartment of Biochemistry, Center of Biological Sciences, Universidade Federal de Santa Catarina, Campus Universitário, Trindade, Florianópolis, SC, 88040-900, Brazil. vivianbneis@gmail.com.ORCID http://orcid.org/0000-0001-6328-431X
Axel Fogaça RosadoDepartment of Biochemistry, Center of Biological Sciences, Universidade Federal de Santa Catarina, Campus Universitário, Trindade, Florianópolis, SC, 88040-900, Brazil.
Gislaine OlescowiczDepartment of Biochemistry, Center of Biological Sciences, Universidade Federal de Santa Catarina, Campus Universitário, Trindade, Florianópolis, SC, 88040-900, Brazil.
Morgana MorettiDepartment of Biochemistry, Center of Biological Sciences, Universidade Federal de Santa Catarina, Campus Universitário, Trindade, Florianópolis, SC, 88040-900, Brazil.
Priscila Batista RosaDepartment of Biochemistry, Center of Biological Sciences, Universidade Federal de Santa Catarina, Campus Universitário, Trindade, Florianópolis, SC, 88040-900, Brazil.
Nicole PlattDepartment of Biochemistry, Center of Biological Sciences, Universidade Federal de Santa Catarina, Campus Universitário, Trindade, Florianópolis, SC, 88040-900, Brazil.
Ana Lúcia S RodriguesDepartment of Biochemistry, Center of Biological Sciences, Universidade Federal de Santa Catarina, Campus Universitário, Trindade, Florianópolis, SC, 88040-900, Brazil.
Universidade Federal de Santa Catarina · BR

Funding

CNPq 158126/2018-1CNPq 421143/2018-5CNPq 449436/2014-4
6 · The paper itself

Abstract

Considering the involvement of GABAergic system in the action of the fast-acting antidepressant ketamine, and that agmatine may exert an antidepressant-like effect through mechanisms similar to ketamine, the purpose of the present study was to evaluate the involvement of GABA

Indexed as

AgmatineAnimalsAntidepressive AgentsDepressionFemaleGABA AgonistsGABA AntagonistsGABAergic Neuronsgamma-Aminobutyric AcidHindlimb SuspensionMiceReceptors, GABAAgmatineAntidepressive AgentsGABA AgonistsGABA Antagonistsgamma-Aminobutyric AcidReceptors, GABAAgmatineAntidepressantGABAKetamineTail suspension test

Identifiers

PMID32447465
OpenAlexW3027215938

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.