ArticleApplied microbiology and biotechnology2020
Multidisciplinary characterization of melanin pigments from the black fungus Cryomyces antarcticus.
Article in Applied microbiology and biotechnology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
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Who cites it
33 citing papers in PubMed, 65 citations in OpenAlex.
- Pigmented fungi derived from hot and cold deserts ecosystems: taxonomy, genomic and biotechnological approach.World journal of microbiology & biotechnology · 2026Review
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- Antioxidants: Mechanisms, Benefits, and the Importance of Extremophilic Microorganisms.Microorganisms · 2026Review
- Synthetic biology for space exploration.NPJ microgravity · 2025Review
- Synthesis and characterization of allomelanin model from 1,8-dihydroxynaphthalene autooxidation.Scientific reports · 2025Article
- Basidiomycete pigments as sustainable food colorants and stabilizers: from fungal biology to industrial potential.Frontiers in microbiology · 2025Review
- 1,8-Dihydroxynaphthalene (DHN) melanin provides unequal protection to black fungi Knufia petricola and Cryomyces antarcticus from UV-B radiation.Environmental microbiology reports · 2024Article
- Deletion of the polyketide synthase-encoding gene pks1 prevents melanization in the extremophilic fungus Cryomyces antarcticus.IUBMB life · 2024Article
- A preliminary survey of the cellular responses of the black fungus Cryomyces antarcticus to long and short-term dehydration.Environmental microbiology reports · 2024Article
- Characterization of melanin fromFrontiers in fungal biology · 2024Article
- Synthesis,Journal of enzyme inhibition and medicinal chemistry · 2023Article
- The hidden rainbow: the extensive biotechnological potential of Antarctic fungi pigments.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2023Review
- The Enigmatic World of Fungal Melanin: A Comprehensive Review.Journal of fungi (Basel, Switzerland) · 2023Review
- Melanin biopolymers from microbial world with future perspectives-a review.Archives of microbiology · 2023Review
- Influence ofFoods (Basel, Switzerland) · 2023Article
- Genetic and Environmental Factors Influencing the Production of Select Fungal Colorants: Challenges and Opportunities in Industrial Applications.Journal of fungi (Basel, Switzerland) · 2023Review
- Production of Fungal Pigments: Molecular Processes and Their Applications.Journal of fungi (Basel, Switzerland) · 2022Review
- Review
- Biosignature stability in space enables their use for life detection on Mars.Science advances · 2022Article
Corrections and comments
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Authors and funding
9 authors at 4 institutions in 4 countries.
Funding
Abstract
Melanin is a natural pigment present in almost all biological groups, and is composed of indolic polymers and characterized by black-brown colorization. Furthermore, it is one of the pigments produced by extremophiles including those living in the Antarctic desert, and is mainly involved in their protection from high UV radiation, desiccation, salinity and oxidation. Previous studies have shown that melanized species have an increased capability to survive high level of radiation compared with the non-melanized counterpart. Understanding the molecular composition of fungal melanin could help to understand this peculiar capability. Here, we aimed to characterize the melanin pigment extracted from the Antarctic black fungus Cryomyces antarcticus, which is a good test model for radioprotection researches, by studying its chemical properties and spectral data. Our results demonstrated that, in spite of having a specific type of melanin as the majority of fungi, the fungus possesses the ability to produce both 1,8-dihydroxynaphthalene (DHN) and L 3-4 dihydroxyphenylalanine (L-DOPA) melanins, opening interesting scenarios for the protection role against radiation. Researches on fungal melanin have a huge application in different fields, including radioprotection, bioremediation, and biomedical applications. KEY POINTS: • Isolation and characterization by multidisciplinary approaches of fungal melanins. • Discovery that pathways for producing DOPA and DHN are both active even in its extreme habitat. • Hypothesis supporting the possibility of using melanin pigment for radioprotection.
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Registered trials
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