Evidence map›Paper›PMID 32447418›Full record

ArticleInternational urogynecology journal2020

First-line treatment of pelvic organ prolapse and discontinuation of pessary treatment.

Janani Kantharooban Umachanger, Mette Ladegaard Marcussen, Henrik Bøggild, Niels Kjærgaard, Karin Glavind

Registry-linked trialAbstract read
PubMed Publisher
In one paragraph

Article in International urogynecology journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06021769 (Longitudinal Assessment of Pessary Experience), which is not on this map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06021769 recruitingnot on this mapstarted 2023, after this paper: background citation

Longitudinal Assessment of Pessary Experience

TypeobservationalSponsorUniversity of VirginiaRan2023 to 2026Enrolled30ConditionsPelvic Organ Prolapse, Stress Urinary IncontinenceArmsObservational only
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Observational
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Janani Kantharooban UmachangerDepartment of Gynecology, Aalborg University Hospital, Aalborg, Denmark. j.kantharooban@rn.dk.ORCID 0000-0002-2601-8132
Mette Ladegaard MarcussenDepartment of Gynecology, Aalborg University Hospital, Aalborg, Denmark.
Henrik BøggildPublic Health and Epidemiology Group, Aalborg University and Unit of Epidemiology and Biostatistics, Aalborg University Hospital, Aalborg, Denmark.
Niels KjærgaardDepartment of Gynecology, Aalborg University Hospital, Aalborg, Denmark.
Karin GlavindDepartment of Gynecology, Aalborg University Hospital, Aalborg, Denmark.
Aalborg University Hospital · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe primary objective of this study was to investigate the percentages of women choosing watchful waiting, pessary use or surgery as first-line treatment of pelvic organ prolapse (POP). Second, the rate and cause of discontinuation of pessary use were investigated.

methodsA retrospective chart review was conducted on 794 patients referred with POP at a Danish tertiary center for urogynecology at Aalborg University Hospital between 1 January 2014 and 31 December 2015. The following data were registered: age, BMI, previous use of a pessary, total number of births, vaginal births, cesarean sections, previous hysterectomy, prolapse surgery and incontinence surgery, smoking, menopause, sexual status and POP-Q stage in the three vaginal compartments. Pessary treatments were evaluated after 3 months. Additional visits, reason for discontinuation and secondary treatment were noted.

resultsFirst-line treatment was surgery in 50%, watchful waiting in 33% and pessary use in 17% of patients. Characteristics associated with choosing surgery instead of a pessary were age < 65 years, previous prolapse surgery, prolapse in the anterior or posterior compartment, and POP-Q stage > 2. Characteristics associated with choosing watchful waiting instead of a pessary were age < 65 years and prolapse in the posterior compartment. A total of 33% discontinued pessary treatment within the first 3 months. Discontinuation was associated with age < 65 years, previous hysterectomy and pelvic surgery, and additional visits. Expulsion of the pessary and pain/discomfort were the main causes of discontinuation.

conclusionThis study showed that 50% of patients referred with POP were treated with conservative treatment (watchful waiting and pessary) and thus more women could probably be treated in primary care.

Indexed as

Pelvic Organ ProlapsePessariesAgedFemaleHumansHysterectomyPregnancyRetrospective StudiesTreatment OutcomeVaginaDiscontinuationPelvic organ prolapsePessarySurgeryTreatmentWatchful waiting

Identifiers

PMID32447418
OpenAlexW3028445895

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.