Evidence map›Paper›PMID 32447000›Full record

ArticleFree radical biology & medicine2020

CYP11A1-derived vitamin D

Anyamanee Chaiprasongsuk, Zorica Janjetovic, Tae-Kang Kim, Robert C Tuckey, Wei Li, Chander Raman, Uraiwan Panich, Andrzej T Slominski

Open access · greenAbstract read
In one paragraph

Article in Free radical biology & medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 1 pooled it
4.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 1 synthesis or guideline pooled it, 46 citations in OpenAlex.

  1. Vitamin D-Related Genes and Thyroid Cancer-A Systematic Review.International journal of molecular sciences · 2022
    Pooled it
  2. Review
  3. Review
  4. Review
  5. The vitamin DAmerican journal of physiology. Cell physiology · 2025
    Article
  6. Review
  7. Evolutionary formation of melatonin and vitamin D in early life forms: insects take centre stage.Biological reviews of the Cambridge Philosophical Society · 2024
    Review
  8. Review
  9. Review
  10. Review
  11. Melatonin/Sericin Wound Healing Patches: Implications for Melanoma Therapy.International journal of molecular sciences · 2024
    Review
  12. Article
  13. Review
  14. Article
  15. Vitamin D and COVID-19: where are we now?Postgraduate medicine · 2023
    Review
  16. Review
  17. Review
  18. Vitamin D Signaling in Psoriasis: Pathogenesis and Therapy.International journal of molecular sciences · 2022
    Review
  19. Metabolic activation of tachysterolFASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2022
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 3 countries.

Anyamanee ChaiprasongsukDepartment of Dermatology, University of Alabama at Birmingham, Birmingham, AL, USA; Faculty of Medicine and Public Health, HRH Princess Chulabhorn College of Medical Science, Chulabhorn Royal Academy, Bangkok, Thailand; Department of Pharmacology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Zorica JanjetovicDepartment of Dermatology, University of Alabama at Birmingham, Birmingham, AL, USA.
Tae-Kang KimDepartment of Dermatology, University of Alabama at Birmingham, Birmingham, AL, USA.
Robert C TuckeySchool of Molecular Sciences, The University of Western Australia, Perth, WA, Australia.
Wei LiDepartment of Pharmaceutical Sciences, University of Tennessee Health Science Center, Memphis, TN, USA.
Chander RamanDepartment of Medicine and Microbiology, Division of Clinical Immunology and Rheumatology, University of Alabama at Birmingham, Birmingham, AL, USA.
Uraiwan PanichDepartment of Pharmacology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Andrzej T SlominskiDepartment of Dermatology, University of Alabama at Birmingham, Birmingham, AL, USA; VA Medical Center, Birmingham, AL, USA. Electronic address: aslominski@uabmc.edu.
University of Alabama at Birmingham · USSiriraj Hospital · THThe University of Western Australia · AUUniversity of Tennessee Health Science Center · US

Funding

Mechanism of action and function of novel secosteroid 20(OH)D3 in the skinR01AR073004 · NIAMS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI ANDRZEJ T SLOMINSKI · 2018 to 2026
$2.9M
Novel Biosynthetic Pathway for Secosteroids and the SkinR01AR052190 · NIAMS · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI POSTLETHWAITE, ARNOLD E, SLOMINSKI, ANDRZEJ T · 2006 to 2013
$2.2M
Significance of metabolic activation of lumisterol in the skinR01AR071189 · NIAMS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI SLOMINSKI, ANDRZEJ T · 2017 to 2021
$1.6M
Role of CRH in skin physiology and pathologyR01AR047079 · NIAMS · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI SLOMINSKI, ANDRZEJ T · 2002 to 2004
$708k
CYP11A1-derived secosteroids as therapeutic agents in UVB induced skin cancerI01BX004293 · VA · BIRMINGHAM VA MEDICAL CENTER · PI SLOMINSKI, ANDRZEJ T · 2019 to 2025
–
BLRD VA I01 BX004293NIAMS NIH HHS R01 AR047079NIAMS NIH HHS R01 AR052190NIAMS NIH HHS R01 AR071189NIAMS NIH HHS R01 AR073004
6 · The paper itself

Abstract

UVB radiation mediates inflammatory responses causing skin damage and defects in epidermal differentiation. 1α,25-Dihydroxyvitamin D

Indexed as

CholecalciferolCholesterol Side-Chain Cleavage EnzymeCell DifferentiationCells, CulturedHumansInflammationKeratinocytesVitamin DCholecalciferolCholesterol Side-Chain Cleavage EnzymeVitamin DEpidermal structureKeratinocyte differentiationPhotobiologyUV Radiation

Identifiers

PMID32447000
PMCPMC7339935
OpenAlexW3026744058

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.