ArticleJournal of neuroscience methods2020
Developing and testing of an air dilution flow olfactometer with known rates of concentration change.
Article in Journal of neuroscience methods, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 11 citations in OpenAlex.
- Psychological states affecting initial pupil size changes after olfactory stimulation in healthy participants.Scientific reports · 2023Article
- Multielectrode recordings of cockroach antennal lobe neurons in response to temporal dynamics of odor concentrations.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2023Article
- Gain control in olfactory receptor neurons and the detection of temporal fluctuations in odor concentration.Frontiers in physiology · 2023Article
- Silencing the odorant receptor co-receptor impairs olfactory reception in a sensillum-specific manner in the cockroach.iScience · 2022Article
- The Performance of Olfactory Receptor Neurons: The Rate of Concentration Change Indicates Functional Specializations in the Cockroach Peripheral Olfactory System.Frontiers in physiology · 2020Article
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
backgroundConcentration is a variable aspect of an odor signal and determines the operation range of olfactory receptor neurons (ORNs). A concentration increase is perceived as an odor stimulus. The role that the rate of concentration increase plays thereby has been studied with electrophysiological techniques in ORNs of the cockroach. A key prerequisite for these studies was the development of an air dilution flow olfactometer that allowed testing the same change in concentration at various rates. NEW
methodThe rate of concentration change was controlled and varied by changing the mixing ratio of odor-saturated and clean air by means of proportional valves. Their input voltages were phase shifted by 180° to hold the mixed air at a particular constant volume flow rate.
resultsUsing this stimulation technique, we identified, in a morphologically distinct sensillum on the cockroach's antenna, antagonistically responding ON and OFF ORNs which display a high sensitivity for slow changes in odor concentration. COMPARISON WITH EXISTING
methodsThe olfactometer is unique because it enables delivering slowly oscillating concentration changes. By varying the oscillation period, the individual effects of the instantaneous odor concentration and its rate of change on the ORNs' responses can be determined.
conclusionsThe olfactometer provides a new experimental approach in the study of odor coding and opens the door for improved comparative studies on olfactory systems. It would be important to gain insight into the ORNs' ability to detect the rate of concentration change in other insects that use odors for orientation in different contexts.
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