Evidence map›Paper›PMID 32446470›Full record

Trial reportThe Journal of pediatrics2020

Effect of State Immunization Information System Based Reminder/Recall for Influenza Vaccinations: A Randomized Trial of Autodialer, Text, and Mailed Messages.

Peter G Szilagyi, Christina S Albertin, Alison W Saville, Rebecca Valderrama, Abigail Breck, Laura Helmkamp, Xinkai Zhou, Sitaram Vangala, L Miriam Dickinson, Chi-Hong Tseng and 7 more

3 registry-linked trialsAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in The Journal of pediatrics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03246100 nacompletednot on this map

Centralized IIS-based Reminder/Recall to Increase Childhood Influenza Vaccination Rates, 2nd Trial in Colorado

TypeinterventionalSponsorUniversity of Colorado, DenverRan2017 to 2019Enrolled25,531ConditionsReminder Systems, Influenza VaccinesArmsReminders
NCT03294473 nacompletednot on this map

Centralized IIS-Based Reminder Recall to Increase Influenza Vaccination Rates in New York State - Second Trial in New York State

TypeinterventionalSponsorUniversity of California, Los AngelesRan2017 to 2018Enrolled70,190ConditionsInfluenza, Human, Orthomyxoviridae Infections, RNA Virus Infections, Virus DiseaseArmsR/R - Autodialers, R/R - Texting, R/R - mailed postcard
NCT06657573 nanot yet recruitingnot on this mapstarted 2024, after this paper: background citation

AI-enabled Vaccine Chatbot for Improving Influenza Vaccination Uptake in Children: a Cluster Randomized Trial

TypeinterventionalSponsorFudan UniversityRan2024 to 2025Enrolled1,200ConditionsInfluenza VaccinesArmsAn AI-enabled chatbot tailored for influenza vaccine consultation
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Trial
  4. Trial
  5. Trial
  6. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Peter G SzilagyiDepartment of Pediatrics, UCLA Mattel Children's Hospital, University of California at Los Angeles, Los Angeles, CA. Electronic address: pszilagyi@mednet.ucla.edu.
Christina S AlbertinDepartment of Pediatrics, UCLA Mattel Children's Hospital, University of California at Los Angeles, Los Angeles, CA.
Alison W SavilleAdult and Child Consortium for Health Outcomes Research and Delivery Science (ACCORDS), University of Colorado School of Medicine and Children's Hospital Colorado, Aurora, CO; Department of Pediatrics, University of Colorado School of Medicine, Aurora, CO.
Rebecca ValderramaDepartment of Pediatrics, UCLA Mattel Children's Hospital, University of California at Los Angeles, Los Angeles, CA.
Abigail BreckDepartment of Pediatrics, UCLA Mattel Children's Hospital, University of California at Los Angeles, Los Angeles, CA.
Laura HelmkampAdult and Child Consortium for Health Outcomes Research and Delivery Science (ACCORDS), University of Colorado School of Medicine and Children's Hospital Colorado, Aurora, CO; Department of Pediatrics, University of Colorado School of Medicine, Aurora, CO.
Xinkai ZhouDepartment of Medicine, Statistics Core, David Geffen School of Medicine, University of California, Los Angeles, CA.
Sitaram VangalaDepartment of Medicine, Statistics Core, David Geffen School of Medicine, University of California, Los Angeles, CA.
L Miriam DickinsonAdult and Child Consortium for Health Outcomes Research and Delivery Science (ACCORDS), University of Colorado School of Medicine and Children's Hospital Colorado, Aurora, CO; Department of Pediatrics, University of Colorado School of Medicine, Aurora, CO.
Chi-Hong TsengDepartment of Medicine, Statistics Core, David Geffen School of Medicine, University of California, Los Angeles, CA.
Jonathan D CampbellDepartment of Clinical Pharmacy, University of Colorado Anschutz Medical Campus, Aurora, CO.
Melanie D WhittingtonDepartment of Clinical Pharmacy, University of Colorado Anschutz Medical Campus, Aurora, CO.
Heather RothColorado Immunization Information System, Colorado Department of Public Health and Environment, Denver, CO.
Cynthia M RandDepartment of Pediatrics, University of Rochester School of Medicine and Dentistry, Rochester, NY.
Sharon G HumistonDepartment of Pediatrics, Children's Mercy, Kansas City, MO.
Dina HoeferNew York State Immunization Information System, New York State Department of Health, New York, NY.
Allison KempeAdult and Child Consortium for Health Outcomes Research and Delivery Science (ACCORDS), University of Colorado School of Medicine and Children's Hospital Colorado, Aurora, CO; Department of Pediatrics, University of Colorado School of Medicine, Aurora, CO.

Funding

Centralized IIS-Based Reminder-Recall to Increase Influenza Vaccination RatesR01AI114903 · NIAID · UNIVERSITY OF COLORADO DENVER · PI KEMPE, ALLISON, SZILAGYI, PETER G · 2015 to 2018
$2.8M
NIAID NIH HHS R01 AI114903
6 · The paper itself

Abstract

objectiveTo evaluate the effect of different modalities of centralized reminder/recall (autodialer, text, mailed reminders) on increasing childhood influenza vaccination. STUDY

designTwo simultaneous randomized clinical trials conducted from October 2017 to April 1, 2018, in New York State and Colorado. There were 61 931 children in New York (136 practices) and 23 845 children in Colorado (42 practices) who were randomized to different centralized reminder/recall modalities-4 arms in New York (autodialer, text, mailed, and no reminder control) and 3 arms in Colorado (autodialer, mailed, and no reminder control). The message content was similar across modalities. Up to 3 reminders were sent for intervention arms. The main outcome measure was receipt of ≥1 influenza vaccine.

resultsIn New York, compared with the control arm (26.6%), postintervention influenza vaccination rates in the autodialer arm (28.0%) were 1.4 percentage points higher (adjusted risk ratio, 1.06; 95% CI, 1.02-1.10), but the rates for text (27.6%) and mail (26.8%) arms were not different from controls. In Colorado, compared with the control arm (29.9%), postintervention influenza vaccination rates for the autodialer (32.9%) and mail (31.5%) arms were 3.0 percentage points (adjusted risk ratio, 1.08; 95% CI, 1.03-1.12) and 1.6 percentage points (adjusted risk ratio, 1.06; 95% CI, 1.02-1.10) higher, respectively. Compared with the control arm, the incremental cost per additional vaccine delivered was $20 (New York) and $16 (Colorado) for autodialer messages.

conclusionsCentralized reminder/recall for childhood influenza vaccine was most effective via autodialer, less effective via mail, and not effective via text messages. The impact of each modality was modest. Compared with no reminders, the incremental cost per additional vaccine delivered was also modest for autodialer messages.

trial registrationClinicalTrials.gov: NCT03294473 and NCT03246100.

Indexed as

Influenza VaccinesReminder SystemsAdolescentChildChild, PreschoolColoradoHumansImmunization ProgramsInfantInfluenza, HumanNew YorkText MessagingInfluenza Vaccinesautodialeinfluenza vaccinereminder/recalltext message

Identifiers

PMID32446470
PMCPMC7518461

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.