Evidence map›Paper›PMID 32446440›Full record

ReviewSeminars in pediatric neurology2020

Recent Developments in Treatment Outcome Measures for Young Children With Autism Spectrum Disorder (ASD).

Rebecca Grzadzinski, Denisse Janvier, So Hyun Kim

Abstract readReview
In one paragraph

Review in Seminars in pediatric neurology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Eye Tracking as a Treatment Monitoring Tool for Autism: A Multilevel Meta-Analysis.Autism research : official journal of the International Society for Autism Research · 2025
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  15. Characterizing social communication among minimally verbal children with autism: An application of item response theory.Autism research : official journal of the International Society for Autism Research · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Rebecca GrzadzinskiUniversity of North Carolina, Carolina Institute for Developmental Disabilities, Chapel Hill, NC. Electronic address: Rebecca_grzadzinski@med.unc.edu.
Denisse JanvierCenter for Autism and the Developing Brain, Weill Cornell Medical College, New York-Presbyterian Hospital, White Plains, NY.
So Hyun KimCenter for Autism and the Developing Brain, Weill Cornell Medical College, New York-Presbyterian Hospital, White Plains, NY.

Funding

Postdoctoral Research in Neurodevelopmental DisordersT32HD040127 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BENJAMIN D PHILPOT, Mark D Shen · 2001 to 2026
$8.5M
NICHD NIH HHS T32 HD040127
6 · The paper itself

Abstract

Significant advancements have been made in early intervention programs for children with Autism spectrum disorder (ASD). However, measuring treatment response for children with ASD is difficult due to the heterogeneity of changes in symptoms, which can be subtle, especially over a short period of time. Here we outline the challenge of evaluating treatment response with currently available measures as well as newly developed or refined measures that may be useful in clinical trials for young children with ASD. Continued development of treatment outcome measures will help the field identify and compare efficacious interventions and tailor treatments for children with ASD.

Indexed as

Behavior TherapyEarly Medical InterventionAdolescentAutism Spectrum DisorderBehavior Rating ScaleChildChild, PreschoolHumansNeuropsychological TestsOutcome Assessment, Health Care

Identifiers

PMID32446440
PMCPMC7248125

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.