Evidence map›Paper›PMID 32446408›Full record

ReviewLancet (London, England)2020

Urinary tract infections in children.

Kjell Tullus, Nader Shaikh

Abstract readReview
In one paragraph

Review in Lancet (London, England), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 96 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
96citing papers in PubMed, 1 pooled it
33.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

96 citing papers in PubMed, 1 synthesis or guideline pooled it, 207 citations in OpenAlex.

  1. Pooled it
  2. Trial
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  9. Review
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  16. Article
  17. Disparities in Urine Testing Among Febrile Children in US Emergency Departments.Journal of racial and ethnic health disparities · 2026
    Article
  18. Article
  19. Article
  20. Article

36 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Kjell TullusRenal Unit, Great Ormond Street Hospital for Children, London, UK. Electronic address: kjell.tullus@gosh.nhs.uk.
Nader ShaikhChildren's Hospital of Pittsburgh, Pittsburgh, PA, USA.
Children's Hospital of Pittsburgh · USUniversity College London · GB

Funding

Biomarkers for Urinary Tract Infection and PyelonephritisR01DK118033 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI SHAIKH, NADER · 2019 to 2024
$2.7M
NIDDK NIH HHS R01 DK118033
6 · The paper itself

Abstract

Urinary tract infections (UTIs) in children are among the most common bacterial infections in childhood. They are equally common in boys and girls during the first year of life and become more common in girls after the first year of life. Dividing UTIs into three categories; febrile upper UTI (acute pyelonephritis), lower UTI (cystitis), and asymptomatic bacteriuria, is useful for numerous reasons, mainly because it helps to understand the pathophysiology of the infection. A single episode of febrile UTI is often caused by a virulent Escherichia coli strain, whereas recurrent infections and asymptomatic bacteriuria commonly result from urinary tract malformations or bladder disturbances. Treatment of an upper UTI needs to be broad and last for 10 days, a lower UTI only needs to be treated for 3 days, often with a narrow-spectrum antibiotic, and asymptomatic bacteriuria is best left untreated. Investigations of atypical and recurrent episodes of febrile UTI should focus on urinary tract abnormalities, whereas in cases of cystitis and asymptomatic bacteriuria the focus should be on bladder function.

Indexed as

Urinary Tract InfectionsAnti-Bacterial AgentsAsymptomatic DiseasesBacteriuriaChildCystitisHumansPyelonephritisRisk FactorsAnti-Bacterial Agents

Identifiers

PMID32446408
PMCPMC13498406
OpenAlexW3027642407

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.