ArticleThe Lancet. Global health2020
Physical multimorbidity, health service use, and catastrophic health expenditure by socioeconomic groups in China: an analysis of population-based panel data.
Article in The Lancet. Global health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 248 papers, 5 of them syntheses that pooled it.
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Who cites it
248 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- Decision aids for the care of patients with multimorbidity: a systematic review.BMC primary care · 2025Pooled it
- Variations in multimorbidity measurement in studies evaluating hospitalisation in older adults: a systematic review.BMC geriatrics · 2025Pooled it
- A computational grounded theory based analysis of research on China's old-age social welfare system.Frontiers in public health · 2025Pooled it
- Factors affecting dysbiosis of the gut microbiota in the elderly and the progress of interventions in traditional Chinese and Western medicine.Frontiers in cellular and infection microbiology · 2025Pooled it
- Core outcome sets for trials of interventions to prevent and to treat multimorbidity in adults in low and middle-income countries: the COSMOS study.BMJ global health · 2024Pooled it
- Pay-it-forward intervention increased pneumococcal vaccine uptake among older adults in China: a randomized controlled trial.BMC medicine · 2026Trial
- Socioeconomic inequalities in self-reported vision impairment among middle-aged and older adults in China: a national longitudinal study from 2011 to 2018.Eye (London, England) · 2026Article
- Composite C-reactive protein-triglyceride-glucose adiposity indices and incident cardiovascular-liver-metabolic multimorbidity: a prospective cohort study.Cardiovascular diabetology · 2026Article
- Plan-related inequalities in costs, disease progression and mortality among hypertensive patients in China.Nature communications · 2026Article
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- Chronic disease comorbidity and its impact on healthcare utilization among older adults in China: a cross-sectional and longitudinal analysis.BMC geriatrics · 2026Article
- Prevalence and determinants of multimorbidity in older Chinese adults: a nationwide cross-sectional study using CLASS data.BMC geriatrics · 2026Article
- Multimorbidity patterns among fragility fracture patients aged 50 + years in China and the US.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2026Article
- Associations of the atherogenic index of plasma and its modified indices with the incidence and progression of cardiovascular-liver-metabolic multimorbidity: a prospective cohort study from UK Biobank.Cardiovascular diabetology · 2026Article
- Associations of nine insulin resistance-related indices with the incidence and progression of cardiovascular-liver-metabolic multimorbidity: a large prospective cohort study.Cardiovascular diabetology · 2026Article
- The bidirectional relationships among multimorbidity, depression, and catastrophic health expenditures in middle-aged and older Chinese adults: random-intercept, cross-lagged panel model.BMC public health · 2026Article
- Multimorbidity, health service use, and health insurance by socioeconomic groups in 31 countries: A multi-cohort study.PLoS medicine · 2026Article
- Frailty predicts the onset and dynamic progression of cardio-renal-metabolic multimorbidity: a multistate modeling analysis from the UK Biobank.Diabetology & metabolic syndrome · 2026Article
- Network analysis of psychological problems in school-attending students aged 6-16 years in China: A comparison between rural and urban areas.Pediatric investigation · 2026Article
188 more citing papers are in PubMed but not listed here.
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Abstract
backgroundMultimorbidity, the presence of two or more mental or physical chronic non-communicable diseases, is a major challenge for the health system in China, which faces unprecedented ageing of its population. Here we examined the distribution of physical multimorbidity in relation to socioeconomic status; the association between physical multimorbidity, health-care service use, and catastrophic health expenditures; and whether these associations varied by socioeconomic group and social health insurance schemes.
methodsIn this population-based, panel data analysis, we used data from three waves of the nationally representative China Health and Retirement Longitudinal Study (CHARLS) for 2011, 2013, and 2015. We included participants aged 50 years and older in 2015, who had complete follow-up for the three waves. We used 11 physical non-communicable diseases to measure physical multimorbidity and annual per-capita household consumption spending as a proxy for socioeconomic status.
findingsOf 17 708 participants in CHARLS, 11 817 were eligible for inclusion in our analysis. The median age of participants was 62 years (IQR 56-69) in 2015, and 5766 (48·8%) participants were male. 7320 (61·9%) eligible participants had physical multimorbidity in China in 2015. The prevalence of physical multimorbidity was increased with older age (odds ratio 2·93, 95% CI 2·71-3·15), among women (2·70, 2·04-3·57), within a higher socioeconomic group (for quartile 4 [highest group] 1·50, 1·24-1·82), and higher educational level (5·17, 3·02-8·83); however, physical multimorbidity was more common in poorer regions than in the more affluent regions. An additional chronic non-communicable disease was associated with an increase in the number of outpatient visits (incidence rate ratio 1·29, 95% CI 1·27-1·31), and number of days spent in hospital as an inpatient (1·38, 1·35-1·41). We saw similar effects in health service use of an additional chronic non-communicable disease in different socioeconomic groups and among those covered by different social health insurance programmes. Overall, physical multimorbidity was associated with a significantly increased likelihood of catastrophic health expenditure (for the overall population: odds ratio 1·29, 95% CI 1·26-1·32, adjusted for sociodemographic variables). The effect of physical multimorbidity on catastrophic health expenditures persisted even among the higher socioeconomic groups and across all health insurance programmes.
interpretationConcerted efforts are needed to reduce health inequalities that are due to physical multimorbidity, and its adverse economic effect in population groups in China. Social health insurance reforms must place emphasis on reducing out-of-pocket spending for patients with multimorbidity to provide greater financial risk protection.
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