Evidence map›Paper›PMID 32445736›Full record

Trial reportThe lancet. Diabetes & endocrinology2020

A telehealth lifestyle intervention to reduce excess gestational weight gain in pregnant women with overweight or obesity (GLOW): a randomised, parallel-group, controlled trial.

Assiamira Ferrara, Monique M Hedderson, Susan D Brown, Samantha F Ehrlich, Ai-Lin Tsai, Juanran Feng, Maren Galarce, Santica Marcovina, Patrick Catalano, Charles P Quesenberry

Erratum issued Registry-linked trialOpen access · greenAbstract readMulticenter StudyRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in The lancet. Diabetes & endocrinology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT06682663 (Evaluation of the Effect of Live Streaming Exercise on the Improvement of Hepatic Steatosis and Fibrosis in Pregnant Women with MASLD and Its Study Based on the Liver-gut Axis Mechanism.), which is not on this map. Cited by 92 papers, 13 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
92citing papers in PubMed, 13 pooled it
8.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06682663 nanot yet recruitingnot on this mapstarted 2024, after this paper: background citation

Evaluation of the Effect of Live Streaming Exercise on the Improvement of Hepatic Steatosis and Fibrosis in Pregnant Women with MASLD and Its Study Based on the Liver-gut Axis Mechanism.

TypeinterventionalSponsorPeking UniversityRan2024 to 2026Enrolled220ConditionsMetabolic Dysfunction-associated Steatotic Liver DiseaseArmsLive Streaming Exercise
3 · Its place in the literature

Who cites it

92 citing papers in PubMed, 13 syntheses or guidelines pooled it, 168 citations in OpenAlex.

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  16. [A randomized controlled trial of weight management based on mobile health techno-logy among overweight or obese pregnant women].Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2025
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32 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Assiamira FerraraDivision of Research, Kaiser Permanente Northern California, Oakland, CA, USA. Electronic address: assiamira.ferrara@kp.org.
Monique M HeddersonDivision of Research, Kaiser Permanente Northern California, Oakland, CA, USA.
Susan D BrownDivision of Research, Kaiser Permanente Northern California, Oakland, CA, USA; Department of Internal Medicine, School of Medicine, University of California, Davis, Sacramento, CA, USA.
Samantha F EhrlichDivision of Research, Kaiser Permanente Northern California, Oakland, CA, USA; Department of Public Health, University of Tennessee Knoxville, Knoxville, TN, USA.
Ai-Lin TsaiDivision of Research, Kaiser Permanente Northern California, Oakland, CA, USA.
Juanran FengDivision of Research, Kaiser Permanente Northern California, Oakland, CA, USA.
Maren GalarceDivision of Research, Kaiser Permanente Northern California, Oakland, CA, USA.
Santica MarcovinaNorthwest Lipid Metabolism and Diabetes Research Laboratories, University of Washington, Seattle, WA, USA.
Patrick CatalanoMother Infant Research Institute, Tufts Medical Center, Boston, MA, USA.
Charles P QuesenberryDivision of Research, Kaiser Permanente Northern California, Oakland, CA, USA.
Kaiser Permanente · USTufts Medical Center · USUniversity of California, Davis · USUniversity of Tennessee at Knoxville · USUniversity of Washington · US

Funding

Translational Research Core - Health Engagement & Action Translational (HEAT)P30DK092924 · NIDDK · KAISER FOUNDATION RESEARCH INSTITUTE · PI Alyce Sophia Adams, HILARY Kessler SELIGMAN · 2011 to 2026
$9.2M
Appropriate Gestational Weight Gain in Overweight/Obese WomenR01HD073572 · NICHD · KAISER FOUNDATION RESEARCH INSTITUTE · PI FERRARA, ASSIAMIRA · 2013 to 2017
$3.2M
Physical Activity in Pregnancy for Intergenerational Obesity PreventionK01DK105106 · NIDDK · UNIVERSITY OF TENNESSEE KNOXVILLE · PI EHRLICH, SAMANTHA F · 2015 to 2021
$782k
Engaging At-Risk Minority Women in Health System Diabetes Prevention ProgramsK01DK099404 · NIDDK · KAISER FOUNDATION RESEARCH INSTITUTE · PI BROWN, SUSAN DENISE · 2014 to 2017
$643k
NICHD NIH HHS R01 HD073572NIDDK NIH HHS K01 DK099404NIDDK NIH HHS K01 DK105106NIDDK NIH HHS P30 DK092924
6 · The paper itself

Abstract

backgroundExcess gestational weight gain (GWG) among women with overweight or obesity synergistically increases their already elevated risk of having gestational diabetes, a caesarean delivery, a large for gestational age infant, and post-partum weight retention, and increases their child's risk of obesity. We investigated whether a primarily telehealth lifestyle intervention reduced excess GWG among women with overweight or obesity.

methodsWe did a randomised controlled trial in five antenatal clinics of Kaiser Permanente; Oakland, San Leandro, Walnut Creek, Fremont, and Santa Clara, CA, USA. Women at 8-15 weeks' gestation with singletons, pre-pregnancy BMI 25·0-40·0 kg/m

findingsBetween March 24, 2014, and Sept 26, 2017, 5329 women were assessed for eligibility and 200 were randomly assigned to the lifestyle intervention group and 198 to the usual care group. Analyses included 199 women in the lifestyle intervention group (one lost to follow-up) and 195 in the usual care group (three lost to follow-up). 96 (48%) women in the lifestyle intervention group and 134 (69%) women in the usual care group exceeded Institute of Medicine guidelines for rate of GWG per week (relative risk 0·70, 95% CI 0·59 to 0·83). Compared with usual care, women in the lifestyle intervention had reduced weekly rate of GWG (mean 0·26 kg per week [SD 0·15] vs 0·32 kg per week [0·13]; mean between-group difference -0·07 kg per week, 95% CI -0·09 to -0·04). No between-group differences in perinatal complications were observed.

interpretationOur evidence-based programme showed that health-care delivery systems could further adapt to meet the needs of their clinical settings to prevent excess GWG and improve healthy behaviours and markers of insulin resistance among women with overweight or obesity by using telehealth lifestyle interventions.

fundingUS National Institutes of Health.

Indexed as

Risk Reduction BehaviorAdultExerciseFemaleFollow-Up StudiesGestational Weight GainHumansObesityOverweightPregnancyPrenatal CareTelemedicineWeight LossYoung Adult

Identifiers

PMID32445736
PMCPMC8886506
OpenAlexW3027770756

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.