Evidence map›Paper›PMID 32445671›Full record

ArticleClinical immunology (Orlando, Fla.)2020

Can Ticagrelor be used to prevent sepsis-induced coagulopathy in COVID-19?

Loukman Omarjee, Olivier Meilhac, Frédérique Perrot, Anne Janin, Guillaume Mahe

Open access · greenAbstract readLetterComment
In one paragraph

Article in Clinical immunology (Orlando, Fla.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Review
  5. Article
  6. Purinergic signaling pathway in severe COVID-19.Current opinion in pharmacology · 2023
    Review
  7. Review
  8. Review
  9. PlateletCells · 2022
    Review
  10. Article
  11. Review
  12. Infections Deaths in the PLATO Trial.TH open : companion journal to thrombosis and haemostasis · 2021
    Article
  13. Article
  14. Article
  15. Review
  16. Large-scale Multi-omic Analysis of COVID-19 Severity.medRxiv : the preprint server for health sciences · 2020
    Article
  17. ST Elevations in the Era of COVID-19.Case reports in cardiology · 2020
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Loukman OmarjeeInserm, NuMeCan Institute (UMR INSERM 1241), Rennes F-35033, France; Univ Rennes, CHU Rennes, INSERM, CIC1414, Clinical Immunology and Vascular Medicine, Rennes F-35033, France. Electronic address: loukman.omarjee@chu-rennes.fr.
Olivier MeilhacUniversité de La Réunion, INSERM U1188, Diabetes atherothrombosis Réunion Indian Ocean (DéTROI), CYROI Plateform, Sainte-Clotilde F-97490, France; CHU de La Réunion, Saint-Pierre F-97410, France.
Frédérique PerrotCellular and Molecular Biology Consultant, Rennes F-35033, France.
Anne JaninInserm, (U942), Paris Diderot University, Sorbonne Paris Cité, Paris F-75018, France.
Guillaume MaheVascular Medicine Unit, Inserm, (Clinical Investigation Center 1414), Univ Rennes, CHU Rennes, Rennes F-35033, France.
CIC Rennes · FRÉcologie Marine Tropicale des Océans Pacifique et Indien · REHôpital Lariboisière · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Coronavirus InfectionsPandemicsPneumonia, ViralSepsisBetacoronavirusCOVID-19HumansSARS-CoV-2TicagrelorTicagrelorCOVID-19Neutrophil extracellular trapsP2Y12 inhibitor, TicagrelorPlatelets – Neutrophils aggregatesSepsis-induced coagulopathyVascular leakage

Identifiers

PMID32445671
PMCPMC7240255
OpenAlexW3028145907

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.